关于医院制剂软件建设的几点思考

为适应新的制剂要求,使制剂工作更严格、规范,提出了加大制剂软件建设包括指导性软件、规范行为软件和记录软件等的建议。     

如何设计制剂软件中各种记录软件

以实例着重探讨了制剂记录软件的设计。其关键在于：根据记录目的,对照验收标准,围绕质控要点列出具体内容,而最终形成文件。     

X射线荧光光光谱分析

评述了我国在2007～2008年X射线荧光光谱,包括质子激发的X射线光谱的发展和应用,内容包括仪器、软件、仪器改造、仪器维护和维修、基础研究和分析方法研究及其应用.     

X射线荧光光谱分析

本文评述了我国在2005年至2006年X射线荧光光谱,包括粒子激发的X射线光谱的发展和应用,内容包括仪器研制、激发源、探测器、软件、仪器改造、仪器维护和维修、样品制备技术、分析方法研究和应用.     

X射线荧光光谱分析

评述了我国在2000年7月-2002年6月间X射线荧光光谱，包括粒子激发的X射线光谱的发展和应用，内容包括仪器研制、激发源、探测器、软件、仪器改造、仪器维护和维修、样品制备技术、分析方法研究和应用。     

溶解热测量实验软件设计

设计编写了用于溶解热测量实验的软件,特点是直观易用,功能较多,可在实验中记录原始数据并图示体系温度的变化;设计了由易到难的几种数据处理方案,学生可根据自己的能力选择。     

超高效液相色谱-静电场轨道阱高分辨质谱快速筛查和确证凉茶中167种非法添加药物

基于质谱数据库,建立了超高效液相色谱-静电场轨道阱高分辨质谱(UHPLC-Orbitrap HRMS)快速筛查和确证凉茶中167种非法添加药物的方法.通过调研,选定了解热镇痛药、糖皮质激素、抗菌药、抗组胺药等167种药物,并利用Orbitrap HRMS和TraceFinder软件采集和记录每种药物的信息,建立高分辨质...     

L-8900氨基酸分析仪分析柱重新填充方法

2008年引进的L-8900高速全自动氨基酸分析仪由于使用过久、维护不当,导致泵1压强过高不能正常运行.通过更换线性过滤器,逆洗分析柱,仍没有解决问题,最后重填分析柱使仪器恢复正常.重填分析柱操作较复杂、容易出错,会造成树脂损失,因此,在重填过程中详细记录拆卸、清洗树脂、安装分析柱的完整过程,为今后工作和同行积累经验.     

基于情境相似性原理的化学反应速率教学研究*

基于改进的微量化学反应速率测定实验,依据情境相似性原理将该实验测定的数据,开发为仿真实验探究软件。为课堂教学中模拟化学反应速率的测定,数据记录、数据分析、整合、图像绘制等过程提供帮助。在情境相似中让学生体验科学研究的过程,挖掘化学实验数据分析的教学价值,理解并建立v=Δc/Δt的关系,体会各种变化曲线的来源。     

1stOpt软件在蔗糖水解实验教学中的应用

将1stOpt软件用于物理化学实验蔗糖水解反应速率常数的测定中，在无需严格记录反应开始时间和测定反应终了旋光度的情况下，通过非线性拟合无需编程及公式变换就可以简单方便准确地得到反应速率常数，避免了传统数据处理方法所带来的人为误差，可以补充和改进物理化学实验的教学。     

TRANSITIONAL FIELD BEHAVIOUR FOR THE MATUYAMA-BRUNHES

Paleomagnetic study from Tongjing basalts, Shandong Province, China, provides a record of the transitional field behaviour for the Matuyama-Brunhes. Based on the record the transitional field configurations are studied. The reasons that make the virtual geomagnetic pole (VGP) at the low latitude are researched.     

环境监测实验室管理系统的开发与应用

基于2005版《计量认证/审查认可(验收)评审准则》要求,为满足环境监测实验室业务流程而设计开发了信息管理系统。该系统主要用于环境监测实验室的资源管理和日常自动化办公。系统采用B/S架构,实现全球化办公运作,能对监测样品的受理、分发、分析、原始记录、监测报告、数据三级审核、报告签发实现全程自动流转,并运用工作流和智能表单设计实现实验室程序文件中各类程序和日常办公事务流程的执行;原始记录和监测报告全部实现自动归档及智能查询;同时根据2005版准则中的要求,对人员、设备、材料、环境要素、记录、质量控制等所有要素全面实施网络化管理。     

CHEMFILE: an in-house information system for the chemical indexing of Abstracts on Health Effects of Environmental Pollutants (HEEP)

The inclusion of a Chemical Abstracts Service (CAS) Registry Number index in HEEP has led to the need for a special database designed to link substance names with their appropriate CAS chemical compound Registry Numbers. Begun in 1968 as a tape record with batch mode updates and few record modification capabilities, the information system, which we call CHEMFILE, has evolved to its current form of disk storage with on-line access for file maintenance.     

Planar Array Transient Infrared Spectroscopy: A New Tool for the Time-Resolved Analysis of Polymers

Summary: Planar array infrared spectroscopy (PA-IR) was used for the first time to record transient infrared (TIRS) spectra. In proof-of-concept experiments, it was demonstrated that PA-TIRS can record high quality spectra of common polymeric samples. It was shown the this new technique allows acquiring spectra in as little as 17 ms, opening the door to high speed, real-time monitoring applications.     

The NCI Drug Information System. 2. DIS Pre-Registry

The Pre-Registry Module of the Drug Information System (DIS) is a staging area through which all new compounds are passed prior to acquisition and testing. Several methods are available for the entry of structures into the Pre-Registry; all involve built-in data validation. Newly entered structures are examined by computer programs for structural novelty and potential for anticancer activity. For those compounds that proceed to acquisition, the various acquisition steps, such as letter writing and record updating, are performed automatically. When a sample is obtained, the entire Pre-Registry record is updated and moved forward into the permanent DIS chemistry files.     

Dielectric spectroscopy on W/O emulsions under influence of shear forces

The dielectric properties of concentrated w/o-emulsions have been investigated, both at rest and during shear. The volume fraction water ranged from 0.50 to 0.95. The time domain dielectric spectroscopy techniques (TDS) was used to record the dielectric spectra, which covered the frequency region from 25 MHz to 2 GHz. In order to simultaneously record rheological and dielectric data a modified viscometer of the coaxial cylinder type was applied.A close connection between the viscosity and the dielectric properties of w/o emulsions is demonstrated. The very large effects of shear both on the static permittivity and the dielectric relaxation time for the emulsion can partially be ascribed to the degree of flocculation in the system. At high shear rates, at which the emulsions are expected to have a low degree of flocculation, the observed dielectric properties differ from those expected from a theoretical model for spherical emulsion droplets.     

Monthly sea surface temperature records reconstructed by δ~(18)O of reef-building coral in the east of Hainan Island, South China Sea

Stable oxygen isotopic compositions of a coral colony of Porites lutea obtained on acore allowed the reconstruction of a 56-a (1943-1998) proxy record of the sea surface tempera-tures. This coral δ~(18)O data are from the east of Hainan Island water (22°20＇N, 110°39＇E), SouthChina Sea. The relationship between δ~(18)O in the skeletal aragonite carbonate and the sea surfacetemperature (SST) is SST=-5.36 δ~(18)O_(PDB)-3.51 (r=0.73, n=470), dδ~(18)O/d(SST)=-0.187‰/℃; and the thermometer was set at monthly resolution. The 56-a (1943-1998) proxy record of thesea surface temperatures reflected the same change trend in the northern part of South China Seaas the air temperature change trend in China.     

Record Multiphoton Absorption Cross‐Sections by Dendrimer Organometalation

Large increases in molecular two‐photon absorption, the onset of measurable molecular three‐photon absorption, and record molecular four‐photon absorption in organic π‐delocalizable frameworks are achieved by incorporation of bis(diphosphine)ruthenium units with alkynyl linkages. The resultant ruthenium alkynyl‐containing dendrimers exhibit strong multiphoton absorption activity through the biological and telecommunications windows in the near‐infrared region. The ligated ruthenium units significantly enhance solubility and introduce fully reversible redox switchability to the optical properties. Increasing the ruthenium content leads to substantial increases in multiphoton absorption properties without any loss of optical transparency. This significant improvement in multiphoton absorption performance by incorporation of the organometallic units into the organic π‐framework is maintained when the relevant parameters are scaled by molecular weights or number of delocalizable π‐electrons. The four‐photon absorption cross‐section of the most metal‐rich dendrimer is an order of magnitude greater than the previous record value.     

The resonance inverse raman effect

Multichannel photoelectric detection has been employed to record the inverse Raman spectrum of a number of organic liquids. The enhanced resonance effect has been shown to operate and is proposed as a method for detecting low molecular concentrations.