共查询到20条相似文献,搜索用时 202 毫秒
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.
1.将十二种芳伯胺和亚硝酸正丁酯或异戊酯在沸苯溶液中反应,合成联苯、各种异构的甲基-、氯-和硝基-联苯以及苯基萘。产率令人满意。2.基于各种因素对联苯产率的影响的详细研究,找出用于合成的最适宜条件。3.实验证明在反应中产生的氢氧化重氮化合物与芳(?)胺偶合而生成的重氮氨基化合物是反应的中间产物之一。但氢氧化重氮化合物直接与苯作用而生成联苯和芳基苯也是可能的;这是在稀溶液中反应的主要途径。反应产物的生成可能是自由基历程。 相似文献
11.
Using chloroacetic acid, p‐hydroxyl aromatic aldehydes 1 and aromatic diamines 3 as starting materials, novel bisbenzimidazoles 5 with unsymmetric structure were synthesized via aryloxyacetic acid intermediates 2 . Four new intermediates 4 and ten target molecules 5 were characterized by FTIR, 1H NMR, 13C NMR, MS and elemental analysis. Different synthetic methods, including one‐pot synthesis and intermittent microwave promotion, were investigated. The research provides a new method and idea for the synthesis of bisbenzimidazoles. 相似文献
12.
以二甲酰亚胺钾3a~3g与2-氯-5-氯甲基吡啶的N原子氧化后得到的2-氯-1-氧-5-氯甲基吡啶发生亲核取代反应, 用传统和微波两种方法合成了7种未见文献报到的化合物N-(2-氯-1-氧-5-吡啶甲基)二甲酰亚胺类化合物4a~4g. 对比两种合成方法, 在常压下, 微波辐射作为反应热源具有用时少、环境友好、易纯化和产率高的特点. 这些目标化合物4a~4g的结构经元素分析结果, IR, GC-MS, 1H NMR, 13C NMR确证. 初步的生物活性测定结果表明, N-(2-氯-1-氧-5-吡啶甲基)二甲酰亚胺类部分化合物具有良好的杀虫活性. 相似文献
13.
A new and efficient method for the preparation of N‐substituted pyrroles from one‐pot Paal‐Knorr condensation has been accomplished using nano‐crystalline sulfated zirconia (SZ) as the catalyst in ethanol at moderate temperature. This new protocol has the advantages of easy availability, stability, reusability and eco‐friendliness of the catalyst, high to excellent yields, simple experimental and work‐up procedure. The synthesized compounds were confirmed through spectral characterization using IR, 1H NMR, 13C NMR and mass spectra. 相似文献
14.
Zhiyong Weng Wei Wei Xiaowu Dong Yongzhou Hu Shufang Huang Tao Liu Xin Xie 《Monatshefte für Chemie / Chemical Monthly》2012,17(8):303-308
Abstract
A series of novel piperidin-4-ol derivatives were designed, synthesized, and evaluated for potential treatment of HIV. The compounds were obtained via an efficient synthetic route in excellent yields and have been characterized by 1H NMR, 13C NMR, MS, and elemental analysis. The CCR5 antagonistic activities of the compounds have also been evaluated. 相似文献15.
Shaik Mahaboob Basha Mavallur Varalakshmi Shaik Thaslim Basha Chintha Venkataramaiah Suban Syed Shafi Chamarthi Naga Raju Wudayagiri Rajendra 《中国化学会会志》2019,66(12):1700-1707
A series of new imidazole‐substituted pyridine‐2‐amine and benzo‐substituted imidazol‐2‐amine 3 – 12 were synthesized by treating various amines 1(a – d) with alkyl/aryl isothiocyanate 2(a‐c) at 60–90°C in isopropyl alcohol without using any catalyst with high yields. The structures of all the newly synthesized compounds were characterized using IR, NMR (1H, 13C), mass, and elemental analyses. All the newly synthesized compounds were screened for their in vitro antioxidant and antimicrobial activities to understand their biological potency. All the title compounds exhibited good antioxidant and antimicrobial activities in vitro when compared to the standard drugs. 相似文献
16.
In this study, a series of benzimidazolium salts were synthesized as unsymmetrical N-heterocyclic carbene (NHC) precursors. Benzimidazolium salts were used for synthesis of the PEPPSI (pyridine enhanced precatalyst preparation stabilization and initiation)-themed, six new Pd-complexes with the general formula [PdX2(NHC)(pyridine)]. The structures of all compounds were characterized by various spectroscopic techniques such as 1H NMR, 13C NMR and FT-IR. The more detailed structural characterization of four of the complexes was determined by single-crystal X-ray diffraction study. The catalytic activities of all Pd-complexes were evaluated in the direct arylation of the 2-acetylfuran and 2-acetylthiophene with aryl bromides in the presence of 1 mol% catalyst loading. 相似文献
17.
Miosz Frydrych Daria Pakua Bogna Sztorch Dariusz Brzkalski Robert E. Przekop Bogdan Marciniec 《Molecules (Basel, Switzerland)》2021,26(14)
The functionalization of mono- and octahydrospherosilicate with vinylboranes and allylboranes via hydrosilylation reaction in the presence of a Karstedt’s platinum (0) catalyst is presented. This is the catalytic route to obtain a new class of silsesquioxanes containing boron atoms in their structure in high yields (>90%) and with satisfactory selectivity. The obtained compounds were fully characterized by spectroscopic (1H, 13C, 29Si NMR) and spectrometric methods (MALDI-TOF-MS), as well as thermal analysis (TGA). The obtained compounds were subjected to thermal tests, characterizing the processes of melting, thermal evaporation, sublimation and thermal decomposition. 相似文献
18.
D. Doddramappa Shridevi Srikantamurthy Ningaiah Narayan U. Kuduva Raad K. Yhya Kuriya M. Lokanatha Rai 《合成通讯》2013,43(24):2869-2875
A solvent-free, clean, and efficient method has been developed for the synthesis of 2,5-disubstituted-1,3,4-thiadiazoles via azines. This approach exploits the synthetic potential of clean reactions and offers many advantages such as excellent product yields, easy isolation of products, and ecofriendly benign reaction conditions. The newly synthesized compounds were analyzed by infrared, 1H NMR, 13C NMR, and elemental analysis. 相似文献
19.
Efficient and Facile Catalyst‐free One‐Pot Synthesis and Characterization of Some Novel Bis(2‐benzothiazole) Derivatives 下载免费PDF全文
A general method for preparation of benzothiazole derivatives including oxidative cyclization of the corresponding Schiff bases was reported. Herein, we have been synthesized a series of new acyclic‐substituted bis(2‐arylbenzothiazoles). Synthesis of analogs substituted in the benzothiazole ring was achieved via the direct condensation reaction of o‐aminothiophenol with some of dialdehyde compounds under catalyst free in high yields. The structure of these products has been fully characterized by physical and spectroscopic data such as IR, 1H‐NMR, 13C‐NMR, UV‐Vis, MS, and CHN analysis. 相似文献
20.
《应用有机金属化学》2017,31(4)
Palladium‐catalysed cross‐coupling reactions are some of the most frequently used synthetic tools for the construction of new carbon–carbon bonds in organic synthesis. In the work presented, Pd(II) complex catalysts were synthesized from palladium chloride and nitrogen donor ligands as the precursors. Infrared and 1H NMR spectroscopic analyses showed that the palladium complexes were formed in the bidentate mode to the palladium centre. The resultant Pd(II) complexes were tested as catalysts for the coupling of organobismuth(III) compounds with aryl and acid halides leading to excellent yields with high turnover frequency values. The catalysts were stable under the reaction conditions and no degradation was noticed even at 150°C for one of the catalysts. The reaction proceeds via an aryl palladium complex formed by transmetallation reaction between catalyst and Ar3Bi. The whole synthetic transformation has high atom economy as all three aryl groups attached to bismuth are efficiently transferred to the electrophilic partner. 相似文献