新生儿头发微量及常量元素测定

采用ＪＹ－７０合并型等离子体光谱仪测定了１０４名健康足月新生儿头发中１４种微量元素和２种常量元素含量。结果表明，新生儿发生中Ｆｅ，Ｃｏ，Ｎｉ，Ｍｎ，Ｃｒ，Ｍｏ，Ｓｒ，Ｖ，Ｃａ和Ｍｇ等元素的含量水平较高；新生儿发Ｆｅ男性显著高于女性，发Ｍｇ则女性高于男性，发Ｓｒ女性高于男性，其它各元素性别间无差异或差异不显著。     

磷块岩的微量元素成分和肥效利用

磷块岩含化学元素２２－２４种。对磷块岩和围岩的微量元素进行了比较，其中一些微量含量较高，若制成磷肥，Ｃｒ，Ｃｕ，Ｍｎ，Ｍｏ，Ａｓ，Ｎｉ，Ｓｒ和Ｖ可通过食物链有益于人体健康，但Ｕ，Ｓｒ则可能带来环境问题。     

ICP—AES用于铋系超导体块材及薄膜的组分分析

本文研究了一个简便，快速的用ＩＣＰ－ＡＥＳＢｉ（Ｐｂ）ＳｒＣａＣｕＰｂＯ，Ｂｉ（Ｐｂ，Ｓｂ）Ｓｒ－ＣａＣｕＯ，Ｂｉ（Ｐｂ，Ｙ）ＳｒＣａＣｕＯ超导体块材及薄膜中Ｂｉ，Ｐｂ，Ｓｂ，Ｙ，Ｓｒ，Ｃａ，Ｃｕ含量的方法。样品溶解在５０％ＨＣｌ及５０％ＨＮＯ３的混合酸中，直接引入等离子体光谱中进行测定。对共存元素的相互干扰及基片成分的干扰进行了研究。分析了大量样品，给出了各组分的挥发情况及Ｐｂ的挥发量与烧结温度     

乌鸡白凤丸微量元素的测定及其意义

用等离子体发射光谱法测定了乌鸡白凤丸中Ｆｅ、Ｍｎ、Ｃｕ、Ｚｎ、Ｃｒ、Ｃｏ、Ｓｅ等元素的含量，并探讨了这些元素与乌鸡白凤丸疗效的关系。     

不同产地高良姜无机元素含量的比较

用等离子体发射光谱法测定了三个不同产地高良姜的元素含量，在２７种被测元素中，除Ａｓ、Ｂｅ、Ｃｒ、Ｍｏ、Ｐｂ、Ｓｂ、Ｔｌ７种元素未被检出外，三个产地的高良姜均含有Ａｇ、Ａｌ、Ｂ、Ｂａ、Ｃａ、Ｃｄ、Ｃｏ、Ｃｕ、Ｆｅ、Ｍｇ、Ｍｎ、Ｎａ、Ｎｉ、Ｓｅ、Ｓｉ、Ｖ、Ｚｎ、Ｋ、Ｐ、Ｓ２０种元素，湛江产的高良姜大多数元素的含量要高于其它两地。Ｚｎ和Ｍｎ两种人体必需微量元素的含量较丰富。     

ICP—AES测定东北虎,梅花鹿等动物毛发中的微量元素

研究了东北虎，梅花鹿等动物毛发中元素的ＩＣＰ－ＡＥＳ分析方法，报道了上述毛发中的Ａｌ，Ｃａ，Ｃｕ，Ｆｅ，Ｍｇ，Ｐ，Ｐｂ，Ｓｒ，Ｚｎ等元素的含量，为研究微量元素与动物仞关系提供了参考。     

海带中生命元素的ICP—AES研究

应用ＩＣＰ－ＡＥＳ技术测定了Ｓｒ，Ｃａ，Ｍｇ，Ｐ，Ｆｅ，Ｃｕ，Ｍｎ和Ｚｎ等８种生命元素在海带中的分布，发现三种分布模式；（１）Ｆｅ，Ｃｕ，Ｍｎ，Ｚｎ在叶状体末端和边缘，固着器末端含量高，其余部位含量低；（２）Ｓｒ和Ｃａ的分布规律与第一类相似，但固着器基部高于固着器末端；（３）Ｍｇ和Ｐ均匀分布。     

用多变量统计分析方法辨识肺癌患者分类中的关键元素(英文)

用逐步判别、主成分分析和聚类方法研究了根据血清和毛发样品中元素含量对正常人和肺癌患者分类中的关键元素．用主成分分析的结果表明,在肺癌患者与正常人的分类中,血清中的Ｃａ,Ｃｒ,Ｃｕ,Ｐ和Ｚｎ是关键元素,而毛发中的Ａｌ,Ｂ,Ｃｒ,Ｐ和Ｓｒ是关键元素．对于正常人和癌症患者元素之间的欧氏距离不同     

12种道地中药中无机元素的含量测定

报道了用Ｘ射线荧光分析法测定的１２种道地中药，９８个不同产地样品中的Ｆｅ、Ｃｕ、Ｚｎ、Ｍｎ、Ｓｒ、Ｃａ、Ｋ含量。结果表明，不同种属，不同产地，不同品种中药元素量存在差异，不同加工方法影响中药中元素含量，同种中药中元素分布模式也不同。     

计算机模式识别法在甲状腺肿瘤患者血清微量元素谱研究中的应用

用马氏距离判别法对５３例甲状腺肿瘤患者和５８例健康人血清中Ｂａ、Ｃｒ、Ｍｇ、Ｍｎ、Ｍｏ、Ｓｒ、Ｚｎ、Ｆｅ、Ｃｕ和Ｃａ等元素含量进行了分类研究,分类准确度达９２．８％。研究结果表明,甲状腺肿瘤病变可能与人体中Ｍｏ、Ｍｎ、Ｆｅ、Ｍｇ、Ｃａ和Ｓｒ含量异常有关。文中还计算了患者和健康人血清元素间的相关系数,并讨论了其差异性。     

延边地区65～108岁健康老人头发中锌、铜、铁、锰、镁的含量

用原子吸收光谱法测定延边地区317名65～108岁老人头发中锌、铜、铁、锰、镁含量，观察不同民族、性别、年龄老人这些元素的差异。结果表明：1.朝鲜旗发锌低于汉族，满族发铜低于汉族、朝鲜族，汉族发镁高于朝鲜族、满族，发铁、发锰在汉、朝、满民族之间无区别。2．汉族、朝鲜族男发锌高于女性，汉族女性发铜高于男性，发铁、发锰、发镁在性别之间无区别。3、90岁组朝鲜族发锰、发镁低于65岁、76岁组，朝鲜族发锌、发铜、发铁在65～108岁之间无统计学意义。     

两种产地的沉香药材及水煎液中6种矿物质元素的分布特征比较

采用火焰原子吸收光谱法(FAAS)测定了两产地(海南、云南)沉香药材中的Zn、Fe、Cu、Mn、Ca和Mg6种矿物质元素的含量。根据样品中矿物质的含量计算矿物质在日服用量下的"中国营养素参考值百分比"(矿物质NRV%),然后绘制日服用量下矿物质NRV标准化分布模式图。结果表明,海南产和云南产沉香中各矿物质元素的含量及矿物质NRV标准化分布模式图都有明显差异。海南产沉香中Ca、Mg、Mn的含量分别约是云南产沉香中Ca、Mg、Mn的2倍,而云南产沉香中Fe的含量约是海南产沉香的4.6倍。海南沉香的原药和水煎液中均以Mn的NRV%最高;云南沉香原药以Fe的NRV%最高,水煎液以Mn的NRV%最高。     

不同产地道地中药中元素含量的比较研究

研究了中药中微量元素Ｆｅ、Ｃｕ、Ｚｎ、Ｍｎ、Ｓｒ含量与产地的关系，结果表明，产地是影响中药中元素含量差异，也是影响中药质量的重要因素。     

Determination of aluminum in large volume parenteral drug products used in total parenteral nutrition therapy by ICP-MS with a dynamic reaction cell

The proposed method was developed for the determination of aluminum (Al) in large volume parenteral (LVP) drug products used in total parenteral nutrition (TPN) therapy. The determination of Al in LVP drug products was performed by an inductively coupled plasma mass spectrometer equipped with a dynamic reaction cell (DRC-ICP-MS). DRC-ICP-MS conditions for the analysis of Al were studied to obtain the best signal to background (S/N) ratios. The interfering polyatomic ions at mass 27 (Al) were reduced by using NH(3) as a reaction gas. The detection limit of Al in a 1% (v/v) HNO(3) aqueous solution was 2 ng/l. The Al contents in LVP drug products obtained by this method were in the range of 1.16-4.33 microg/l and were less than 25 microg/l, that is, the regulation value of Food and Drug Administration (FDA). In order to trace the origin of Al in LVP drug products, each part of the LVP drug product, which is composed of three chambers, was investigated. However, a clear difference of the Al contents in each chamber was not observed. Furthermore, the Al contents in injection bags were quantified. Although the Al contents in injection bags were relatively high (in the range of 27.5-33.6 microg/g), dissolution of Al from the injection bags was not observed in the stability testing. From all of these results, it was concluded that the Al contents in the LVP drug products investigated originated in the amount of the Al in each raw material.     

56种药材内有害元素As、Hg的含量比较

分析并比较了56种中药内有害元素As、Hg的含量，本文可供临床用药时参考。     

Determination of important flavour precursor compounds (Amadori compounds) in cigarettes by LC-MS/MS

A simple and rapid determination of two Amadori compounds in cigarettes, 1-deoxy-1-L-proline-D-fructose (Fru-Pro) and 1-deoxy-1-L-alanine-D-fructose (Fru-Ala), which are the important intermediates in Maillard reaction, was achieved by HPLC-MS/MS. Eighty-eight commercial brand cigarettes of 5 different styles were employed to investigate their diversities on Fru-Pro and Fru-Ala. The contents of Fru-Pro and Fru-Ala in all cigarette samples correlate with each other. Comparison of the contents of two compounds reveals a substantial difference for different cigarettes: the contents of the two Amadori compounds in Chinese flue-cured cigarettes are remarkably higher than in British flue-cured, American, Japanese and Chinese blend cigarettes. This might be beneficial for using these two compounds as characteristic markers to identify the flavor-specific Chinese flue-cured cigarettes.     

Primary study on the application of Serum Pharmacology in Chinese traditional medicine

In the paper, two main methods, which are Serum Pharmacology and Traditional Pharmacology, were adopted to study Chinese traditional medicine, such as Ginkgo biloba extract (GBE), ginsenosides (GS) and compound GG (GBE + GS), pharmacology in vitro. The results showed that there were evident difference between the results of Serum Pharmacology and that of Traditional Pharmacology. There was no significant difference between the drug effect of crude GS on nitric oxide (NO) production in ECV304 and that of crude GBE, and the drug effect of GG was superior to that of GS and GBE, respectively. But, compared with GBE serum, the GS serum up-regulation of NO production in ECV304 increased significantly, and the GG serum up-regulation of the NO production in ECV304 was inferior to that of GS serum and GBE serum significantly. The results suggested that Serum Pharmacological study should be adopted in the pharmacological investigation on the Chinese traditional medicine and the drug screening of the Chinese traditional medicine.     

Isolation of two new coumarin glycosides from Notopterygium forbesii and evaluation of a Chinese crude drug, qiang-huo, the underground parts of N. incisum and N. forbesii, by high-performance liquid chromatography

From the ether extract of the underground part of Notopterygium forbesii, two new coumarin glycosides, bergaptol-O-beta-D-glucopyranoside and 6'-O-trans-feruloylnodakenin, were isolated along with known compounds including seven furanocoumarins, two dihydrofuranocoumarins, a sterol glucoside and two phenolic compounds. Analysis of their contents by high-performance liquid chromatography (HPLC) revealed that the underground part of N. forbesii contained large amounts of p-hydroxphenethyl anisate (0.7%), bergaptol glucoside (0.2%), nodakenin (2%) and 6'-O-trans-feruloylnodakenin (0.7%) and a lesser amount of notopterol (0.08%), while that of N. incisum contained a large amount of notopterol (1.2%) and less amounts of the others. The characteristic difference in chemical composition between the two species enabled us to identify the respective botanical sources of a Chinese crude drug, Qiang-huo derived from N. incisum and N. forbesii by HPLC.     

中药化州橘红乙酸乙酯提取物中微量元素的分布及含量

以乙酸乙酯为溶剂萃取分离了中药化州橘红水煎液的有机成分；测定了提取物中元素的分布及含量，分析了不同微量元素在提取物中富集程度的差别。并由此说明了中药微量元素与中药所含的有机成分是有密切关系的。     

新生儿肺炎血中元素含量的变化

对５０例新生儿肺炎患儿和５０例正常新生儿进行了全血中元素锌、铁、钙、镁、铜、锰含量的对比观察，结果发现新生儿肺炎患儿血液中锌、铁、钙、镁４种元素均显著低于正常新生儿，血铜、锰与正常组无显著性差异．提示新生儿肺炎患儿血锌、铁、钙、镁的代谢方面均存在一定缺陷，认为新生儿肺炎患儿合理补充微量元素，对治病有益处。