Measurement uncertainty procedures revisited: Direct determination of uncertainty and bias handling

This article is based on a lecture presented at the Analytica Conference, where the basic principles for evaluating and expressing the uncertainty of analytical measurements, as set out in the guides published by ISO and EURACHEM, were reviewed, and the inventory of procedures and tools for effective implementation of these principles was examined. While the emphasis in the lecture was on basic principles, this article presents a more detailed elaboration of one of the main practical procedures outlined in the lecture: direct determination of uncertainty and handling of bias.     

Organic synthesis in a changing world

This article is based on a lecture presented to the Chemical Society of Japan at Wasada University on March 27, 2002, by Professor Steven V. Ley. The lecture, "Organic Synthesis in a Changing World," was a comprehensive account of the ongoing research efforts of professor Ley's group in the development and application of solid-supported reagents and scavengers for use in organic synthesis.     

Zaubervorlesung mit Salvador Dalí. Chemie‐Edutainment

During the past 10 years the “Magic chemistry” lecture was conducted in Erlangen. Due to an increasing professionalization of the lecture and especially the underlying information concept, we could emphasize the seriousness of this event. We combine scientific education and entertainment to an “edutainment” concept. We hope to show in an exemplary way, how fun and experimental natural sciences can be combined in a big live event.     

高分子物理本科教学之我见

高分子物理是一门物理课,其内涵为高分子物质的结构、结构演变与各层次结构单元的运动规律,而非聚合物的"结构与性能"关系.这门课为解释结构与性能关系提供基础概念与理论,但不是"结构与性能"关系本身.这样的定位决定了高分子物理课不应采用系统教学法,而应当采用逻辑教学法,即从一个不证自明的公理(逻辑起点)出发,沿着一条主线,依次导出、建立全部理论体系.在高分子物理中,这个逻辑起点就是长链结构,主线就是熵弹性.故该门课程应按熵弹性这条主线展开.对现行高分子物理课程内容进行分析,大多数内容均可用熵弹性的主线串起来,另外少部分内容也与熵弹性有密切关系.应根据这两点对现行课程体系与教学方法进行改造,为课程各项内容之间建立逻辑关系,方便学生的学习与应用.     

Recent developments on the fluorinase from Streptomyces cattleya

This is a summary of a lecture presented at the 100th Anniversary, Moissan Symposium in Paris on Friday, 10 November 2006. The lecture highlighted recent developments on the enzyme structure, mechanism and biotransformation prospects of the fluorinase enzyme identified in 2002 from the bacterium Streptomyces cattleya. Over-expression of the enzyme has allowed it to be used as a catalyst for ¹⁸F-incorporation during the synthesis of potential ligands for positron emission tomography (PET) applications.     

创新完善集体备课制度，提升有机化学实验教学质量

集体备课作为有机化学实验教学中一个不可或缺的重要环节,数十年来,我们始终坚持并不断创新发展,使集体备课的内容更加全面、形式更多样化、实效性更强。集体备课促进了教师自身素质和教学能力提高,加快了一流实验教学团队建设,推动了实验教学内容、教学方法、教学手段以及实验室管理的创新发展,保障了有机化学实验教学质量稳步提升。     

New antitumor agents from inhibitors of folate-dependent enzymes

This lecture summarizes our recent investigations in folate analogue chemistry, which have resulted in the synthesis of several extremely promising chemotherapeutic agents for the treatment of solid tumors. Much of this work has been published previously, this review lecture is concerned with some of the chemical developments of interest in the field of heterocyclic chemistry.Department of Chemistry, Princeton University, Princeton, New Jersey, 08544. Published in Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1332–1344, October, 1995. Original article submitted September 1, 1995.     

Die Zaubervorlesung: „Chemie am laufenden Band”︁

Every year at the start of the winter semester at the Friedrich Alexander University Erlangen‐Nürnberg, the lecture „Chemical Magic Tricks”︁ is held. In time and due to generation changes, the nature of this event has changed. From a classical experimental lecture it was transformed into a multi media show, which is very popular among the public and even made its way into television. Our aim with this article is to pass our experience and further information required on to those interested to present such an advertisement event for chemistry.     

Versatility of the pyridazine system: Chemistry and biology

In accordance with the title of my lecture, I am going to briefly illustrate our researches on pyridazine derivatives active in different biological areas.     

“We try not to call them batteries”

Linda Nazar, awarder with the August Wilhelm von Hofmann lecture at GDCh Wissenschaftsforum Darmstadt, talks about batteries, future energy storage systems and the pity of dropping her crystal ball.     

Reactivity of solids

A review of studies of reactivities of solids is presented, concentrating on localization and autolocalization phenomena. Some examples of feed-back and structure of the reaction zone are given. Plenary lecture     

Theory and experiment in mass spectrometry: a perspective on the relationship between computational modelling and experiment in gas-phase ion chemistry

In this lecture/paper we will discuss the somewhat complicated relationship between theory and experiment in molecular science in general and mass spectrometry in particular, illustrated by some recent literature examples.     

On the chemical nature of iodinating species

This review was presented as a plenary lecture at the International Symposium on Radioiodines. The chemical nature of iodinating species are reviewed with emphasis on biological iodinations and goitrogens.     

Scholarship, Education, and the Internet

A lecture demonstration of primary kinetic isotope effect using the bromination of acetone and acetone-d₆ is described.     

Why do we need more powerful methods in environmental trace analysis of the elements and what scope exists?

Due to the fact that main parts of this contribution have already been published elsewhere only its abstract is presented. Some of the most innovative publications which are the basis of the lecture are cited     

M. S. Tswett and the discovery of chromatography I: Early work (1899–1903)

Summary On the occasion of the 90th anniversary of the Warsaw lecture of M. S. Tswett representing the first report on the chromatographic technique, this two-part article outlines the evolution of the method. This part deals with Tswett's early work in 1899–1901 and his research in 1901–1903 leading to the lecture at Warsaw. The second part will deal with the fundamental twin papers of 1906, with his book of 1910, summarizing all his activities related to the investigation of plant pigments and to the development of chromatography, and with a few special questions related to Tswett's scientific activities in this field.Part II of this article will be published in the next month's issue ofChromatographia.     

Historical demonstration experiments in Analytical Chemistry

Some examples of the use of lecture demonstration throughout the early history of chemistry are presented with examples chosen from Analytical Chemistry. In order to limit this vast subject, mainly Scandinavian sources have been used. This is rather natural as the early history of Analytical Chemistry is so much dominated by the works of the Swedish chemist Torbern Bergman. An interesting source at early lecture experiments are the books on natural magic, which were very popular in the 17 th and 18 th centuries. These books contain recipes for household remedies mingled with scientific observations. From the 18 th century most of the examples have been taken from Torbern Bergman’s works. Received: 15 January 1996 / Accepted: 29 January 1996     

Historical demonstration experiments in Analytical Chemistry

Some examples of the use of lecture demonstration throughout the early history of chemistry are presented with examples chosen from Analytical Chemistry. In order to limit this vast subject, mainly Scandinavian sources have been used. This is rather natural as the early history of Analytical Chemistry is so much dominated by the works of the Swedish chemist Torbern Bergman. An interesting source at early lecture experiments are the books on natural magic, which were very popular in the 17 th and 18 th centuries. These books contain recipes for household remedies mingled with scientific observations. From the 18 th century most of the examples have been taken from Torbern Bergman’s works. Received: 15 January 1996 / Accepted: 29 January 1996     

快速色谱

基于柱液相色谱和薄层色谱之间的关系,讨论如何为快速色谱选择流动相,并介绍此技术手工操作的步骤.     

关于科学探究教学若干问题的思考

针对科学探究教学实践中提出的"什么是科学探究?"、"什么样的知识需要探究?"、"探究就比讲授好吗?"、"探究需要什么样的引导"等问题,从理论上进行了探讨。