Regulation of the lumen of a resistance blood vessel by mechanical stimuli

The flow in a vessel able to regulate its lumen under the action of mechanical stimuli, the variation of the pressure difference between the inner and outer surfaces of the vessel wall and the blood flow velocity, is described. This ability is determined by the effect of the mechanical stimuli on the degree of activation of smooth muscle cells in the vessel wall. In order to describe the active properties of the wall, two controlling parameters which have the sense of the concentration of free calcium ions in the cytoplasm of smooth muscle cells and the average concentration of nitric oxide in the smooth muscle layer, are introduced. The approach proposed makes it possible to estimate both the degree of participation of each mechanical stimulus in vessel lumen regulation and the result of interaction of two differently directed vascular responses. The calculations show that both the magnitude and direction of the radius response to a mechanical stimulus depend on the initial state of the vessel wall. The role of the vessel wall sensitivity to mechanical stimuli in the stabilization of the blood flow-rate and the variation of the radius along the vessel is considered.     

纳米碳酸钙作为润滑脂添加剂的摩擦学性能及流变行为研究

使用碳化法制备出三种具有不同粒径的纳米碳酸钙颗粒,利用透射电镜(TEM)和X射线衍射仪(XRD)对其形貌及结构组成进行表征.通过UMT-2摩擦学试验机及RS6000流变仪分别考察了纳米颗粒作为润滑脂添加剂的摩擦学性能及流变学行为,并通过X射线多功能电子能谱仪(XPS)对磨斑表面进行分析.结果表明:所制备的三种纳米颗粒均为方解石结构,可以显著提高基础脂的减摩抗磨性能;添加剂浓度及添加剂尺寸均会影响润滑脂最终的摩擦学性能;在最佳添加浓度和尺寸条件下,能够同时获得最佳的抗磨减摩性能;过高的添加剂浓度会影响润滑脂的结构稳定性,进而影响其摩擦学性能;三种纳米添加剂在磨斑表面形成以碳酸钙为主要成分的润滑膜,纳米颗粒物理性质的差异可能导致其摩擦学性能的差异.     

Simulation of detonation wave interaction using an ignition and growth model

A kinetics based detonation model has been integrated with an existing object oriented hydrocode. The model has been demonstrated to correctly predict the shock initiation of explosives and captures key features such as the von Neumann pressure spike and reaction zone. Comparisons to experimental flyer plate data for both primary and secondary class explosives have been performed and key features such as detonation wave form and resulting target disk velocities are reproduced. Simulations have also been performed representing the interaction of various mechanical waves. First, the interaction of detonation waves, a key process in energetic systems, is simulated. Next, the response of an established detonation wave to an explosive that has been preconditioned by a weak compression wave is modeled. These have been carried out to determine the utility of the existing kinetic schemes for such problems.     

泡沫材料对冲击波的衰减特性

对冲击波与开式、闭式泡沫作用及其在空气中的传播特性开展实验研究,探讨不同结构的泡沫材料对冲击波衰减的力学特征。通过定量分析泡沫材料对冲击波的超压峰值、正冲量的损失,分析冲击波入射、反射、透射的正冲量。实验结果表明, 泡沫材料对冲击波的衰减体现在对冲击波的反射衰减等方面,其中开式泡沫对冲击波的衰减效果比闭式泡沫稍好,且它们衰减冲击波的具体力学过程也不尽相同。     

Propagation of Lamb waves in transversely isotropic thermoelastic diffusive plate

The constitutive relations and field equations for anisotropic generalized thermoelastic diffusion are derived and deduced for a particular type of anisotropy, i.e. transverse isotropy. Green and Lindsay (GL) theory, in which, thermodiffusion and thermodiffusion–mechanical relaxations are governed by four different time constants, is selected for study. The propagation of plane harmonic thermoelastic diffusive waves in a homogeneous, transversely isotropic, elastic plate of finite width is studied, in the context of generalized theory of thermoelastic diffusion. According to the characteristic equation, three quasi-longitudinal waves namely, quasi-elastodiffusive (QED-mode), quasi-massdiffusive (QMD-mode) and quasi-thermodiffusive (QTD-mode) can propagate in addition to quasi-transverse waves (QSV-mode) and the purely quasi-transverse motion (QSH-mode), which is not affected by thermal and diffusion vibrations, gets decoupled from the rest of the motion of wave propagation. The secular equations corresponding to the symmetric and skew symmetric modes of the plate are derived. The amplitudes of displacements, temperature change and concentration for symmetric and skew symmetric modes of vibration of plate are computed numerically. Anisotropy and diffusion effects on the phase velocity, attenuation coefficient and amplitudes of wave propagation are presented graphically in order to illustrate and compare the analytically results. Some special cases of frequency equation are also deduced from the existing results.     

Numerical simulation on vapor absorption by wavy lithium bromide aqueous solution films

Numerical simulation has been made on heat and mass transfer of vapor absorption by wavy lithium bromide aqueous solution films. The velocity fields and interface positions are obtained by VOF model. Solitary waves are generated by periodically disturbed inflow boundary. Based on these, the temperature and concentration fields are obtained with a stationary interface shape. The effect of solitary waves on the heat and mass transfer across the film is investigated. It is shown that due to the mixing of circulation and stretch of large film thickness, the gradient of concentration and absorption rate decrease for solitary wave region. The region of capillary waves shows a significant amount of absorption enhancement. The percentage of absorption for the different regions is quantified.     

Breakdown of parametric fluid oscillations

Under the conditions of Faraday resonance the breakdown of oscillations of the free surface of a homogeneous fluid and of the interface in a two-layer fluid in a rectangular vessel is investigated. Experimentally, for several modes of surface and internal waves, the breakdown frequencies are measured and it is observed that on approaching these frequencies the waves intensely disintegrate. As in the theory of parametric oscillations of mechanical systems with one degree of freedom, the theoretical modeling is based on the assumption of the determining role of dissipative factors. For breaking Faraday waves an equivalent damping coefficient is introduced and estimated from experimental resonance curves. The applicability of the approach proposed is demonstrated with reference to a mechanical system with one degree of freedom: a physical pendulum with the suspension point oscillating vertically.     

Dynamic stress concentration around two interacting coated nanowires with surface/interface effect

In coated nanowires, the surface/interface effects are particularly prominent due to a larger ratio of surface area to volume. In this paper, the effect of surface/interface stress on the macroscopic dynamic stress concentration around two nanowires under anti-plane shear waves is studied. The analytical solutions of displacements around the coated nanowires, in the coating layers, and inside the nanowires are expressed by wave function expansion method. The expanded mode coefficients are determined by satisfying the boundary conditions at the two interfaces around the nanowires. To accomplish the superposition of displacement fields, the addition theorem for cylindrical wave function is employed. Analyses show that the effect of interface properties on the dynamic stress is significantly related to the wave frequency, the material properties of nanowires and coating layers, and the relative position and distance between the two nanowires. If the wires and coating layers are softer, the dynamic stress decreases greatly, and the interface effect on the dynamic stress is also little. The results may be potentially useful for providing information on the mechanical properties and interactions among array of nanowires under different external mechanical stimulus.     

Numerical simulations of the process of multiple shock–flame interactions

Based on a weighted essentially nonoscillatory scheme, the multiple interactions of a flame interface with an incident shock wave and its reshock waves are numerically simulated by solving the compressible reactive Navier–Stokes equations with a single-step Arrhenius chemical reaction. The two-dimensional sinusoidally perturbed premixed flames with different initial perturbed amplitudes are used to investigate the effect of the initial perturbation on the flame evolutions. The results show that the development of the flame interface is directly affected by the initial perturbed amplitudes before the passages of reshock waves, and the perturbation development is mainly controlled by the Richtmyer–Meshkov instability(RMI). After the successive impacts of multiple reshock waves, the chemical reaction accelerates the consumption of reactants and leads to a gradual disappearance of the initial perturbed information. The perturbation developments in frozen flows with the same initial interface as those in reactive flows are also demonstrated.Comparisons of results between the reactive and frozen flows show that a chemical reaction changes the perturbation pattern of the flame interface by decreasing the density gradient,thereby weakening the baroclinic torque in the flame mixing region, and therefore plays a dominant role after the passage of reshock waves.     

Love waves in a layer on a regularly laminated half-space

We theoretically study the existence conditions for Love waves in a layer with arbitrary thickness and arbitrary physical and mechanical properties on a regularly laminated half-space. Also we analyze the behavior of the dispersion curves depending on the physical and geometrical properties of the layer and the mechanical properties of the upper layer of the half-space. It is demonstrated that the behavior of the spectrum and the ranges of surface waves can efficiently be controlled by varying the thickness of the layer.Translated from Prikladnaya Mekhanika, Vol. 40, No. 9, pp. 131–136, September 2004.     

超声波对金属材料性能影响实验研究

通过对紫铜和低碳钢在超声波作用下材料特性的实验研究，探讨此类材料的一些特殊表现诸如屈服点降低，硬化率降低和延伸率降低等．建立了一套超声波材料拉伸实验系统，给出材料特性变化的实验数据并对这些特殊现象的形成机理进行初步探讨．给出了韧性金属材料在超声波作用下的本构方程，并与实验结果相比较，结果表明理论分析与实验结果一致     

Mechanical wave momentum from the first principles

Axial momentum carried by waves in a uniform waveguide is considered based on the conservation laws and a kind of the causality principle. Specifically, we examine (without resorting to constitutive data) steady-state waves of an arbitrary shape, periodic waves which speed differs from the speed of its form and binary waves carrying self-equilibrated momentum. The approach allows us to represent momentum as a product of the wave mass and the wave speed. The propagating wave mass, positive or negative, is the excess of that in the wave over its initial value. This general representation is valid for mechanical waves of arbitrary nature and intensity. The finite-amplitude longitudinal and periodic transverse waves are examined in more detail. It is shown in particular, that the transverse excitation of a string or an elastic beam results in the binary wave. The closed-form expressions for the drift in these waves functionally reduce to the Stokes’ drift in surface water waves (a half the latter by the value). Besides, based on the general representation an energy–momentum relation is discussed and the physical meaning of the so-called “wave momentum” is clarified.     

A three-dimensional numerical study on instability of sinusoidal flame induced by multiple shock waves

The instabilities of a three-dimensional sinusoidally premixed flame induced by an incident shock wave with Mach = 1.7 and its reshock waves were studied by using the Navier–Stokes(NS) equations with a single-step chemical reaction and a high resolution, 9th-order weighted essentially non-oscillatory scheme. The computational results were validated by the grid independence test and the experimental results in the literature. The computational results show that after the passage of incident shock wave the flame interface develops in symmetric structure accompanied by large-scale transverse vortex structures. After the interactions by successive reshock waves, the flame interface is gradually destabilized and broken up, and the large-scale vortex structures are gradually transformed into small-scale vortex structures. The small-scale vortices tend to be isotropic later.The results also reveal that the evolution of the flame interface is affected by both mixing process and chemical reaction. In order to identify the relationship between the mixing and the chemical reaction, a dimensionless parameter, η, that is defined as the ratio of mixing time scale to chemical reaction time scale, is introduced. It is found that at each interaction stage the effect of chemical reaction is enhanced with time.The enhanced effect of chemical reaction at the interaction stage by incident shock wave is greater than that at the interaction stages by reshock waves. The result suggests that the parameter η can reasonably character the features of flame interface development induced by the multiple shock waves.     

Acceleration waves and second sound in a perfect fluid

The evolutionary behaviour of acceleration waves of arbitrary shape in a perfect fluid is investigated. The theory employed allows two coupled mechanical and temperature acceleration waves to propagate with finite wavespeeds. New results are described for waves entering isothermal regions but where the exterior flow velocity is non-zero.     

Propagation velocities of elastic waves in saturated soils

Based on the wave equations established by the authors, the characteristics of propagation velocities of elastic waves in saturated soils are analyzed and verified by ultrasonic test in laboratory and seismic survey in the field. The results provide theoretical basis for the determination of physical and mechanical parameters of saturated soils using propagation velocities of elastic waves, especially P-wave Velocity.     

INTRACELLULAR SOLITARY PULSE CALCIUM WAVES IN FROG SYMPATHETIC NEURONS

IntroductionCalciumionlevelsinintracellularsympatheticneuronsplayacontrollingroleinthetransmissionprocessesofvarioussignals,includingneuron_transmittersecretion ,regulationofmembraneexcitability ,inductionofgeneexpression ,etc .[1]However,howisthecytoplasmiccalciumconcentrationinneuronsregulated ?WehavealreadyknownthattheraiseincalciumconcentrationinXenopuslaevisoocyteismainlyoriginatedfromtheinfluxofCa2 outofcalciumstoresintheendoplasmicreticulum ,whichisinitiatedwiththestimulationofextrace…     

Hysteretic linear and nonlinear acoustic responses from pressed interfaces

An analysis of the linear and nonlinear acoustic responses from an interface between rough surfaces in elastoplastic contact is presented as a model of the ultrasonic wave interactions with imperfect interfaces and closed cracks. A micromechanical elastoplastic contact model predicts the linear and second order interfacial stiffness from the topographic and mechanical properties of the contacting surfaces during a loading–unloading cycle. The effects of those surface properties on the linear and nonlinear reflection/transmission of elastic longitudinal waves are shown. The second order harmonic amplitudes of reflected/transmitted waves decrease by more than an order of magnitude during the transition from the elastic contact mode to the elastoplastic contact mode. It is observed that under specific loading histories the interface between smooth surfaces generates higher elastoplastic hysteresis in the interfacial stiffness and the acoustic nonlinearity than interfaces between rough surfaces. The results show that when plastic flow in the contacting asperities is significant, the acoustic nonlinearity is insensitive to the asperity peak distribution. A comparison with existing experimental data for the acoustic nonlinearity in the transmitted waves is also given with a discussion on its contact mechanical implication.     

DYNAMIC MODEL OF SELF-OSCILLATING GELS AND THE CONTROLLABILITY ANALYSIS

自振荡凝胶是一类在Belousov-Zhabotinsky化学反应（BZ反应）驱动下能够产生周期性收缩和膨胀大变形的智能软材料,简称为BZ凝胶,在微型激励器、传感器、药物释放、仿生材料等领域有着广泛的应用前景。基于BZ化学反应的Oregonator模型以及凝胶变形的力平衡方程,建立了由二阶微分方程表示的BZ凝胶的简化动力学模型,并通过对BZ凝胶的振荡动力学模型的分析,发现其在动力学相轨迹空间内呈现出稳定的周期性极限环振荡,进而利用改进的打靶法求得了BZ凝胶的振荡周期解,系统研究了反应物浓度、催化剂效率和链状高分子的亲水性等可控系统参数对其振荡形式、周期和幅值的影响。结果表明,只有在特定的系统参数取值下,BZ凝胶才能发生持续的周期性振荡;随着这些参数的改变,BZ凝胶的振荡形式、周期和幅值均产生规律性变化。证明了对自振荡凝胶实施周期性调控在理论上是可行的。     

剪应力对培养内皮细胞表面ATP浓度的调节

剪应力信号转导是目前细胞生物力学的研究热点之一。Ca^2＋作为一种第二信使在剪应力信号转导中扮演了重要角色，钙信号转导是通过胞内自由Ca^2＋浓度变化来实现的。胞内Ca^2＋浓度的大小不仅依赖于细胞承受剪应力的大小，同时依赖于细胞外ATP的浓度。本文采用剪应力诱发内皮细胞分泌ATP的时变模型，通过对平行平板流动腔中的ATP浓度场进行数值模拟，分析了剪应力对培养内皮细胞表面ATP浓度的影响。结果表明，剪应力诱发的ATP分泌明显影响细胞表面附近ATP的浓度；剪应力、对流和扩散效应、ATP的水解作用共同决定了细胞外表面附近ATP的浓度。这一结果提示，剪应力大小并非剪应力信号转导过程中的唯一决定因素；剪应力的作用、激动剂的浓度改变共同参与了剪应力信号转导。     

气相爆轰波绕射流场显示研究

采用基于红宝石激光器（波长694.3 nm）的纹影系统,对气相爆轰波绕射进行了初步的流场显示研究。采用单色激光和合适半带宽（15 nm）的滤光片,有效地消除了爆轰波自发光对流场显示的影响。合理设置激光器同步控制系统的触发延时,得到了序列的爆轰波阵面纹影照片。结果表明:图像清晰地显示了爆轰波阵面的诱导激波、横波及化学反应区。当爆轰波在左尖点处绕射,受稀疏波作用,诱导激波与化学反应区明显分离,导致爆轰波衰减为爆燃。分离的诱导激波和折皱的化学反应区在纹影图上清晰可见。诱导激波在垂直支管右壁面反射,诱导二次起爆。畸变爆轰波在水平和垂直支管中均发生马赫反射。提高初压,爆轰波受分叉口几何属性的影响减小,畸变爆轰波在水平和垂直支管下游较易恢复为自持爆轰波。