Gold Nanoparticles‐Based DNA Logic Gate for miRNA Inputs Analysis Coupling Strand Displacement Reaction and Hybridization Chain Reaction

The molecular level DNA logic gates assisted by nanomaterials hold great promise for disease diagnosis applications. However, designing convenient and sensitive logic gates for molecular diagnostics still remains challenging. In this work, a DNA logic gate platform for miRNA inputs analysis based on the observation of localized surface plasmon resonance variation of gold nanoparticles (AuNPs) is fabricated. As a demonstration, two biomarkers to differentiate indolent and aggressive forms of prostate cancer, miR‐200c and miR‐605, are selected as examples of logical inputs. In addition, five DNA probes are designed according to strand displacement reaction and hybridization chain reaction which are required for DNA logical operation. Since target miRNA inputs are able to trigger DNA structural transformations, which are further used to precisely regulate salt‐induced AuNPs aggregation, miRNA inputs information can be converted to the information of AuNPs states as outputs. This developed system performs amplified detection of low‐abundant target miRNAs without the requirement of any enzymes. In addition, single base‐pair mismatched miRNAs can be effectively differentiated. High‐order logic gates can also be developed with further modifications. Therefore, the DNA AND logic gate is successfully constructed with flexible operations, which has potential in biochemical study and disease diagnosis.     

基于掺锡As2S8条波导的全光逻辑门研究

实验研究了掺锡As2S8条波导的光阻断效应,提出一种新型的基于掺锡As2S8波导的全光逻辑门方案,并试制了掺锡As2S8条波导全光逻辑门,实验结果显示该逻辑门具有良好的波形特性,表明该材料适合做全光逻辑门,具有一定的应用潜力.     

Quantum Logic Networks for Probabilistic Teleportation of an Arbitrary Three-Particle State

The scheme for probabilistic teleportation of an arbitrary three-particle state is proposed. By using single qubit gate and three two-qubit gates, efficient quantum logic networks for probabilistic teleportation of an arbitrary three-particle state are constructed.     

Quantum Logic Networks for Probabilistic Teleportation of an Arbitrary Three-Particle State

The scheme for probabilistic teleportation of an arbitrary three-particle state is proposed. By using single qubit gate and three two-qubit gates, efficient quantum logic networks for probabilistic teleportation of an arbitrary three-particle state are constructed.     

基于非线性光纤环镜的40Gb/s可重构光逻辑门

提出了一种新型的基于非线性光纤环镜(NOLM)的可重构全光逻辑门实现方案。传统的基于NOLM的全光逻辑利用自相位调制效应或交叉相位调制效应,透射传输函数重构的自由度低,可实现的逻辑门种类较少。该方案在传统的结构基础上,分析了NOLM中探测光的偏振态的演化,以及输入光偏振态和环内偏振控制器对NOLM的传输特性的影响。理论分析和数值仿真结果表明在考虑NOLM中的非线性偏振旋转效应的情况下,可以更加自由地构建不同透射传输函数,从而利用单一NOLM结构,仅通过调节偏振控制器,即能够可重构地实现绝大部分基础组合逻辑。实验中,完成了两路40Gb/s的数据信号之间的"非"、"与"、"或"、"或非"、"同或"、"异或"等各种基础组合逻辑,验证了方案的可行性。     

High‐Fidelity Hybrid Quantum Gates between a Flying Photon and Diamond Nitrogen‐Vacancy Centers Assisted by Low‐Q Single‐Sided Cavities

High‐fidelity universal quantum gates are crucial in quantum computing. Three high‐fidelity universal quantum gates, namely the hybrid controlled NOT gate, the hybrid Toffoli gate, and the hybrid Fredkin gate, on a flying photon qubit and diamond nitrogen‐vacancy (NV) centers, assisted by low‐Q single‐sided cavities, are presented. Errors due to the imperfection of the practical input–output process are detected to improve the fidelity of these quantum gates, which therefore relaxes the requirement on their implementation, since strong coupling is no longer mandatory. In addition, quantum gates have the advantage that they can work faithfully even when the resonant condition among the NV center, the photon, and the cavity is not strictly satisfied, or the NV centers are not identical. The performance and success probability of these quantum gates are analyzed, finding that these schemes are feasible with current technology.     

Logical operations using phenyl ring

Exploiting the effects of quantum interference we put forward an idea of designing three primary logic gates, OR, AND and NOT, using a benzene molecule. Under a specific molecule-lead interface geometry, anti-resonant states appear which play the crucial role for AND and NOT operations, while for OR gate no such states are required. Our analysis leads to a possibility of designing logic gates using simple molecular structure which might be significant in the area of molecular electronics.     

用腔场中的二能级势阱离子实现量子逻辑门

利用光腔中的势阱粒子同时与外激光场和腔场发生相互作用的特性，我们提出了一种量子逻辑门的实现方案。在该方案中，我们采用文献[10-12]中的模型。文献[11-12]中实现的逻辑门是以离子内态和运动态作为量子比特，腔态充当辅助比特在计算过程中保持在基态。而[10]要求离子内态保持为基态，利用离子运动态和腔态构成量子比特。与文献[10-12]不同的是，我们实现的量子逻辑门是以粒子内态和腔态作为比特，而势阱离子的运动态作为辅助比特始终保持在基态。而且，我们对该方案的实验要求进行了讨论。     

Quantum Circuit Synthesis using a New Quantum Logic Gate Library of NCV Quantum Gates

Since Controlled-Square-Root-of-NOT (CV, CV^?) gates are not permutative quantum gates, many existing methods cannot effectively synthesize optimal 3-qubit circuits directly using the NOT, CNOT, Controlled-Square-Root-of-NOT quantum gate library (NCV), and the key of effective methods is the mapping of NCV gates to four-valued quantum gates. Firstly, we use NCV gates to create the new quantum logic gate library, which can be directly used to get the solutions with smaller quantum costs efficiently. Further, we present a novel generic method which quickly and directly constructs this new optimal quantum logic gate library using CNOT and Controlled-Square-Root-of-NOT gates. Finally, we present several encouraging experiments using these new permutative gates, and give a careful analysis of the method, which introduces a new idea to quantum circuit synthesis.     

Quantum Fourier Transform-Based Arithmetic Logic Unit on a Quantum Processor

This study proposes and construct a primitive quantum arithmetic logic unit (qALU) based on the quantum Fourier transform (QFT). The qALU is capable of performing arithmetic ADD (addition) and logic NAND gate operations. It designs a scalable quantum circuit and presents the circuits for driving ADD and NAND operations on two-input and four-input quantum channels, respectively. By comparing the required number of quantum gates for serial and parallel architectures in executing arithmetic addition, it evaluates the performance. It also execute the proposed quantum Fourier transform-based qALU design on real quantum processor hardware provided by IBM. The results demonstrate that the proposed circuit can perform arithmetic and logic operations with a high success rate. Furthermore, it discusses in detail the potential implementations of the qALU circuit in the field of computer science, highlighting the possibility of constructing a soft-core processor on a quantum processing unit.     

Recent Advances in Common Transition Metal-Based Single-Atom Nanozymes and Their Applications in Pollutant Detection and Degradation

Nanozymes can be used as favorable substitutes for natural enzymes because of their strong catalytic activity and good stability. At the same time, research on single-atom catalysts (SACs) with isolated metal atoms as active centers is also in full swing, showing excellent performance in a variety of catalytic reactions. With the in-depth study of SACs, people have a comprehensive understanding of them and put forward the concept of single-atom nanozymes (SAzymes) by combining nanozymes with SACs. As a new type of nanomaterial, SAzymes have attracted great interest due to their remarkable catalytic activity and rapid energy conversion. However, most applications of SAzymes are mainly in the fields of biomedicine and biosensing, and less research has been done in the field of the environment. Based on the amazing ability of nanozymes to detect and degrade pollutants, SAzymes are also used in the environmental field, and even they will show better capabilities. This review mainly analyses common transition metal-based SAzymes and describes their applications in the field of environmental pollutants.     

Field programmable spin-logic based on magnetic tunnelling elements

Spin-dependent tunnelling elements are widely studied due to their possible application in electronic devices. Here we focus on field programmable logic devices. We introduce the concepts and demonstrate experimentally the functionality of reprogrammable logic gates based on spin-dependent tunnelling elements. We further extend this demonstration to logic gates consisting of micron-sized tunnelling elements.     

可编程光学并行模糊逻辑门

提出了可级联的光学并行模糊逻辑门系统，十六种模糊逻辑运算可通过编程偏振半波片的状态而得到实现，语言中给出了实验结果。     

Quantum Logic Gates and Cluster States with Four-level Atoms in Cavity QED

We propose a model to implement the two-qubit quantum logic gates, i.e., the quantum phase gate and the Controlled-NOT gate, and generate the atomic qubits cluster states with a large detuned interaction between four-level atoms and a single-mode cavity field. In the presented protocol, the quantum information is encoded on the stable ground states of the atoms, and the effect of decoherence from atomic spontaneous emission is negligible. In addition, the interaction between atoms and the cavity is large detuned, and the cavity is only virtually excited. Therefore, the scheme is insensitive to the cavity decay. The experimental feasibility of our proposal is also discussed.     

Coumarin Based Fluorescent Probe for Colorimetric Detection of Fe<Superscript>3+</Superscript> and Fluorescence Turn On-Off Response of Zn<Superscript>2+</Superscript> and Cu<Superscript>2+</Superscript>

A new coumarin based Schiff-base chemosensor-(E)-7-(((8-hydroxyquinolin-2-yl)methylene) amino)-4-methyl-2H-chromen-2-one (H ₁₁ L) was synthesized and evaluated as a colorimetric sensor for Fe³⁺ and fluorescence “turn on-off” response of Zn²⁺ and Cu²⁺ using absorption and fluorescence spectroscopy. Upon treatment with Fe³⁺ and Zn²⁺, the absorption intensity as well as the fluorescence emission intensity increases drastically compared to other common alkali, alkaline earth and transition metal ions, with a distinct color change which provide naked eye detection. Formation of 1:1 metal to ligand complex has been evaluated using Benesi-Hildebrand relation, Job’s plot analyses, ¹H NMR titration as well as ESI-Mass spectral analysis. The complex solution of H ₁₁ L with Zn²⁺ ion exhibited reversibility with EDTA and regenerate free ligand for further Zn²⁺ sensing. H ₁₁ L exhibits two INHIBIT logic gates with two different chemical inputs (i) Zn²⁺ (IN1) and Cu²⁺ (IN2) and (ii) Zn²⁺ (IN1) and EDTA (IN2) and the emission as output. Again, an IMPLICATION logic gate is obtained with Cu²⁺ and EDTA as chemical inputs and emission as output mode. Both free ligand as well as metal-complexes was optimized using density functional theory to interpret spectral properties. The corresponding energy difference between HOMO-LUMO energy gap for H ₁₁ L, H₁₁L-Zn²⁺ and H₁₁L-Cu²⁺ are 2.193, 1.834 and 0.172 eV, respectively.     

基于逻辑器件响应特性的自治布尔网络调控

自治布尔网络已成功应用于随机数产生、基因调控、储备池计算等领域.为了在应用中合理选择器件使输出更好地满足各应用的需求,本文研究了自治布尔网络中的逻辑器件响应特性变化时,自治布尔网络输出状态随之变化的规律,结果显示逻辑器件响应特性变化可以调控自治布尔网络输出在周期和混沌之间转变,且能改变自治布尔网络输出序列的复杂程度.进一步观察了逻辑器件响应特性和链路延时二维参数空间中输出序列复杂程度的分布,结果显示快的逻辑门响应特性可以增强高复杂序列在链路延时参数空间的分布范围.同时研究了自治布尔网络中任意逻辑器件的响应特性单独变化对网络输出状态的影响,结果显示不同节点的器件响应特性对序列复杂程度的调控能力有差异.研究表明,逻辑器件响应特性可以调控网络输出序列复杂程度,快的响应特性有利于高复杂混沌的稳定产生.     

飞秒激光直写光量子逻辑门

量子比特在同一时刻可处于所有可能状态上的叠加特性使得量子计算机具有天然的并行计算能力,在处理某些特定问题时具有超越经典计算机的明显优势.飞秒激光直写技术因其具有单步骤高效加工真三维光波导回路的能力,在制备通用型集成光量子计算机的基本单元—量子逻辑门中发挥着越来越重要的作用.本文综述了飞秒激光直写由定向耦合器构成的光量子比特逻辑门的进展.主要包括定向耦合器的功能、构成、直写和性能表征,集成波片、哈达玛门和泡利交换门等单量子比特逻辑门、受控非门和受控相位门等两量子比特逻辑门的直写加工,并对飞秒激光加工三量子比特逻辑门进行了展望.     

基于半导体光纤环形腔激光器的新型全光AND门和NOR门

提出了一种新型的基于半导体光纤环形腔激光器(SFRL)中同时发生的四波混频效应和交叉增益调制效应同时实现全光AND门和NOR门方案，并建立了这种全光逻辑门完整的宽带理论模型.通过数值模拟的方法，研究了输入信号光峰值功率及SFRL中两个耦合器的耦合比对这种全光逻辑门输出特性的影响. 关键词： 半导体光纤环形腔激光器 全光逻辑门 四波混频 交叉增益调制     

光致异构全光逻辑门理论与实验研究

基于双光抽运探测模型，利用偶氮苯聚合物光致异构和光致双折射效应，建立了全光逻辑门的理论分析模型，提出了一种新颖的全光逻辑门设计方案.该方案基于输入抽运光和信号光的强度或偏振态，设计了“与”门、“或”门、“异或”门和“异或非”门等基本功能的全光逻辑门.以掺杂分散红1(DR1)的聚甲基丙烯酸甲酯(PMMA)薄膜为样品进行实验，得到了比较好的逻辑门运算实验结果，与理论分析相符合.     

A three‐level dark state and double‐control single‐photon logic gates via quantum coherent control

Multilevel quantum coherence and its quantum‐vacuum counterpart, where a three‐level dark state is involved, are suggested in order to achieve new photonic and quantum optical applications. It is shown that such a three‐level dark state in a four‐level tripod‐configuration atomic system consists of three lower levels, where constructive and destructive quantum interference between two control transitions (driven by two control fields) arises. We point out that the controllable optical response due to the double‐control tunable quantum interference can be utilized to design some fascinating new photonic devices such as logic gates, photonic transistors and switches at quantum level. A single‐photon two‐input XOR logic gate (in which the incident “gate” photons are the individual light quanta of the two control fields) based on such an effect of optical switching control with an EIT (electromagnetically induced transparency) microcavity is suggested as an illustrative example of the application of the dark‐state manipulation via the double‐control quantum interference. The present work would open up possibility of new applications in both fundamental physics (e.g., field quantization and relevant quantum optical effects in artificial systems that can mimic atomic energy levels) and applied physics (e.g., photonic devices such as integrated optical circuits at quantum level).