共查询到18条相似文献,搜索用时 156 毫秒
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两种单光纤光镊捕获效果的数值仿真与实验研究 总被引:1,自引:0,他引:1
采用一种基于时域有限差分(FDTD)的数值算法,仿真计算了抛物线形和大锥角形两种新型单光纤光镊的出射光场,并在稳态场下通过对麦克斯韦应力张量积分求得介质球在两种光场中受到的光阱力,得到大锥角型光纤端产生的光阱力较大的结论;讨论了不同介质球大小、折射率,光纤探针形状对光阱力的影响.在实验中这两种光纤探针都实现了对水中酵母菌细胞的捕获,且采用流体力学法对抛物线形和大锥角形二种新型单光纤光镊产生的光阱力进行了标定.结果表明:基于FDTD数值仿真方法计算受力与实验结果一致,并且这种计算光纤光镊产生的光阱力的方法简单.适用;且抛物线形和大锥角形光纤探头都具备构成单光纤光镊的条件. 相似文献
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光镊是研究单分子生物物理特性的独特工具, 因而光镊设备的研发是一个极为重要的课题. 本文根据矩阵光学, 对基于有限远共轭显微镜的光镊操控光路进行计算, 得出了阱位径向操控和轴向操控方程, 并分析了光束调控系统、 共焦系统后置透镜和耦合透镜安装位置误差及物镜轴向位置调整对光镊阱位径向及轴向操控精度的影响. 计算结果显示, 当物镜初级像面和耦合透镜像方焦面完全重合, 光束调控系统和耦合透镜的距离误差对阱位径向和轴向操控精度没有影响. 光镊系统元器件定位不准时, 基于无限远共轭显微镜光镊的阱位径向操控误差和轴向操控误差都小于基于有限远共轭显微镜光镊的阱位径向操控误差和轴向操控误差. 当光镊耦合透镜定位误差控制在小于10 mm时, 基于有限远共轭显微镜光镊的径向和轴向操控误差分别小于5.9%和11.4%, 有限远共轭显微镜仍然存在改造为光镊的价值.本文理论为基于有限远共轭显微镜的光镊设计、改造和操控提供理论和实验指导.
关键词:
光镊
光学设计
矩阵
误差 相似文献
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分别从理论和实验上分析了光纤表面倏逝场强度的分布(z=10 nm, 100 nm, 500 nm,1 000 nm),研究了微米级光纤光镊对微球的操纵。实验中把直径为125 m的普通单模光纤拉制成锥腰直径为2 m的锥形光纤。当光纤通光时,在光纤锥区倏逝场的作用下,直径3 m的聚苯乙烯微球保持平衡状态,并且光纤附近的微球被吸引到光纤表面,以5.3 m /s的速度沿着光束的传播方向运动。这个实验不仅实现了对微球的成功捕获,而且验证了光纤光镊的力学作用。光纤光镊对微球的无接触、无损伤操纵,将在生物传感领域有潜在的应用。 相似文献
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《光学学报》2010,(2)
论述了一种与光镊结合的显微拉曼光谱即"光镊-显微拉曼光谱"系统的构建方案。给出了利用该系统测得的活细胞(大白鼠血细胞,酵母细胞)的微区拉曼光谱,并将红外光镊束缚下的Ar+激光激发的血细胞的拉曼光谱,与用单一Ar+激光光镊束缚并同时激发的血细胞拉曼光谱,以及血细胞直接贴在基底上的拉曼光谱进行了分析对比。实验表明,前者比后两种实验方案的血细胞拉曼光谱信号有显著提高。分析了红外1064 nm光镊激光和可见514.5 nm Ar+激光对活细胞的损伤效应,发现高功率的红外激光对细胞的损伤作用远小于低功率的Ar+激光。并将该系统应用于碳纳米管材料分析,获得了单壁碳纳米管的拉曼光谱。 相似文献
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We develop a pair of tapered-tip single fiber optical tweezers, and study its multi-trapping characteristic. The finite difference time domain method is employed to simulate the trapping force characteristic of this pair of single fiber optical tweezers, and the results show that the number of trapped particles depends on the refractive index and the size of the particles. The trapping force of this pair of tapered-tip single fiber optical tweezers is calibrated by the experimental method, and the experimental results are consistent with the theoretical calculation results. The multi-trapping capability realized by the tapered-tip single fiber optical tweezers will be practical and useful for applications in biomedical research fields. 相似文献
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Optical tweezers have developed into a versatile and widely used tool; compared with the traditional optical tweezers, optical traps built with a single optical fiber provide a more flexible solution towards compact, integrated multiple traps. But the single optical tweezers have their own short comings—the manipulation working on the micro-particles is not non-contact, because of the fabrication method of the optical fiber probe. However we propose new single fiber multi-optical tweezers which are simple, low-cost and can manipulate micro-particles in a non-contact manner and non-invasively. 相似文献
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Recently, interest in nano-manipulation using the evanescent wave generated by nano-objects has been growing, but the analyses of manipulation flexibility and performance haven't been solved. In this paper the near-field optical trap utilizing a tapered metalized probe used in NSOM is described in detail. By employing a generalization of the conservation law for momentum using three-dimensional FDTD method, rigorous calculations of field distributions and trapping forces in near-field region are conducted. Calculations show that the particle with radius larger than the aperture is pushed away from the metal-coated fiber probe, while it tends to be trapped in larger effective region as its radius becoming smaller. The particle that is placed very near the aperture and around two field peaks intends to be dragged to the aperture edge, while the particle placed at other position tends to be attracted to the center surface of the probe tip. Furthermore, a preferable method using the combination of the near-field optical fiber probe and the AFM metallic probe is proposed, for more efficient non-contact manipulation and better observation of one single nano-particle. The analyses of trapping potential along the probe axis and the near-field distribution show the possibility of particle trapping. 相似文献
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《中国光学快报(英文版)》2017,(6)
We propose and demonstrate a novel single fiber optical tweezer based on a graded-index multimode fiber(GIMMF), which works with a free length GIMMF(30 cm). We achieve a three-dimensional stable trap of yeast cells by using the GIMMF optical tweezers. Compared with the single-mode fiber optical tweezers,the GIMMF optical tweezers possess large optical trapping forces. Owing to the freedom of the GIMMF length,the fabrication of the GIMMF optical tweezers is simple, repeatable, and highly efficient. The GIMMF tweezers have the penitential to become a new member of the single fiber optical tweezers family and have a wide range of applications in the medical and biological cytology fields. 相似文献
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A method for optical formation and controllable manipulation of particle and cell patterns using a tapered optical fiber is demonstrated. With a laser beam at 980‐nm wavelength launched into the fiber, different sized silica particles were formed into particle patterns (both one‐dimensional chains and two‐dimensional arrays) with different particle numbers by optical binding. The formed particle patterns can be controllably manipulated in three dimensions. Using yeast cells as an example, it was demonstrated that the method is applicable for the formation of biological cell patterns, without damage to the yeast cell viability. This method provides a new facile way for biophotonic and biological researches with particles and cells in a highly organized manner. 相似文献
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Optical and Quantum Electronics - Twin-core fiber optical tweezers (TCFOT) can be simulated using finite difference beam propagation method. We chose a tapered TCFOT and calculated its far-field... 相似文献
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A double tapered optical fiber sensor based on evanescent field-effect and surface modification technology was introduced in this work. Whether the liquid and gas molecules had polarities or not, they all could be detected by the sensors modified in different silane coupling agents. At the same time, the sensing characters of the single mode optical fiber with three different tapering lengths were researched, and it came to a conclusion that the optical fiber sensor had stronger evanescent field effect and higher sensitivity when length of tapered fiber was 30 mm. The functionalized tapered fibers modified by 3-aminopropyltrimethoxy silane (APTES) or 3-methylpropenylacyloxy propyltrimethoxy silane (MPAPTES), were employed to detect the polar or nonpolar molecules which had corresponding features. Further, the results of quantitative tests showed that the fiber optic sensor was sensitive to the change of the ethanol concentration and the characteristic peaks of the absorption power spectra could reach to 3–5 dB. 相似文献