A validated Quantitative HPTLC Method for Analysis of Biomarkers in Enicostemma littorale Blume

JPC – Journal of Planar Chromatography – Modern TLC - Enicostemma littorale (Chota-Chirayata or Mamejava) is a glabrous perennial herb belonging to the family Gentianaceae. This plant...     

HPTLC Method for Quantification of Isovitexin in the Whole-Plant Powder of Enicostemma littorale Blume

JPC – Journal of Planar Chromatography – Modern TLC - A sensitive and accurate high-performance thin-layer chromatographic method has been developed, validated, and used for...     

Littordial F,a novel phloroglucinol meroterpenoid from the leaves of Psidium littorale

Littordial F (1), a novel meroterpenoid with an unique 6/8/9/4-tetracyclic nucleus, was isolated from the leaves of Psidium littorale. The structure of 1 was established by spectroscopic data, and its absolute configuration was confirmed by computational ¹³C NMR and optical rotation data. Compound 1 exhibited potential cytotoxic activities on A549, B16, and HepG-2 cell lines. A plausible biosynthetic pathway for littordial F was proposed.     

Densitometric HPTLC Analysis of Juglone,Quercetin, Myricetin,Rutin, Caffeic Acid,and Gallic Acid in Juglans regia L.

JPC – Journal of Planar Chromatography – Modern TLC - Asensitive, selective, and precise high-performance thin-layer chromatography (HPTLC) method was developed for simultaneous...     

Thin-Layer Chromatographic Determination of Diazepam,Phenobarbitone, and Saccharin in Toddy Samples

JPC – Journal of Planar Chromatography – Modern TLC -     

Densitometric Determination of Naproxen,and of Naproxen Methyl Ester,its Impurity,in Pharmaceutical Preparations

JPC – Journal of Planar Chromatography – Modern TLC - A chromatographic–densitometric method has been established for identification and quantification of...     

Densitometric Determination of Omeprazole,Pantoprazole, and their Impurities in Pharmaceuticals

JPC – Journal of Planar Chromatography – Modern TLC - A method has been developed for separation of omeprazole and pantoprazole, and their impurities omeprazole sulfone and...     

Videodensitometric HPTLC Determination of Fleroxacin,Sparfloxacin, and Cinoxacin in Tablets

JPC – Journal of Planar Chromatography – Modern TLC - A new, simple, accurate, and rapid high-performance thin-layer chromatographic method has been developed for the determination of...     

Isolation and Densitometric HPTLC Analysis of Rutin,Narcissin, Nicotiflorin,and Isoquercitrin in Caragana spinosa Shoots

JPC – Journal of Planar Chromatography – Modern TLC - Athin-layer chromatographic (TLC) method was used for the quantification of four dominant flavonoids (rutin, narcissin,...     

A New TLC Method for Quantification of Paraquat,Diquat, Difenzoquat,Mepiquat and Chloromequat in Water

JPC – Journal of Planar Chromatography – Modern TLC - We report improved separation of the highly toxic contact herbicides paraquat, diquat, difenzoquat, mepiquat, and chloromequat by...     

Simultaneous Determination of Marmin,Skimmianine, Umbelliferone,Psoralene, and Imperatorin in the Root Bark of Aegle Marmelos by High-Performance Thin-Layer Chromatography

JPC – Journal of Planar Chromatography – Modern TLC - Aegle marmelos (Rutaceae) has gained traditional therapeutic importance owing to their coumarins (umbelliferone, psoralene, marmin,...     

Analysis of a New Potent Hallucinogen, 25-B-NBOMe,in Blotters by High-Performance Thin-Layer Chromatography

JPC – Journal of Planar Chromatography – Modern TLC -     

A New,Convenient Method for Determination of Mangiferin,an Anti-Diabetic Compound,in Mangifera indica L.

JPC – Journal of Planar Chromatography – Modern TLC - A simple, precise, and rapid HPTLC method has been established for quantitative determination of the bioactive marker compound...     

Simultaneous Determination of Pioglitazone,Metformin, and Glimepiride in Pharmaceutical Preparations using HPTLC Method

JPC – Journal of Planar Chromatography – Modern TLC - A simple, precise, and accurate high-performance thin-layer chromatography (HPTLC) method for the simultaneous determination of...     

Simultaneous HPTLC Analysis of Atorvastatin Calcium,Ramipril, and Aspirin in a Capsule Dosage Form

JPC – Journal of Planar Chromatography – Modern TLC - A simple, sensitive, accurate, and precise high-performance thinlayer chromatographic method has been established for simultaneous...     

Triarylborane-Appended Anils and Boranils: Solid-State Emission,Mechanofluorochromism, and Phosphorescence

Herein, the design, synthesis, optical properties, and mechanofluorochromism characteristics of a series of conjugates having covalently linked triarylborane (TAB) and anil/boranil units (TAB-anil: 1 a – 3 a and TAB-boranil: 1 – 3 ) are reported. The electronic interactions between TAB and anil/boranil in 1 a – 3 a and 1 – 3 were fine-tuned by changing the boryl moiety's position on the phenyl spacer connecting the BMes₂ (Mes=mesityl) and anil/boranil units. A boryl moiety at the meta position ( 1 a ) of the phenyl spacer stabilizes the enolic form (E-OH), whereas a boryl moiety at the para position ( 2 a and 3 a ) stabilizes the keto form (Z-NH) in the solid state. However, in solution 1 a , 2 a , and 3 a exhibit keto–enol tautomerism in both ground and excited states. Compounds 1 a – 3 a and 1 – 3 show red-shifted absorption compared with 4 a and 4 , which are devoid of TAB moieties, which indicate effective participation of an empty p orbital on the boron center in 1 a – 3 a and 1 – 3 . Compounds 1 and 2 showed fluorescence variations in response to external stimuli such as mechanical grinding. Long phosphorescence lifetimes of 18–46 ms were observed for compounds 1 – 3 . The observed optical properties of 1 a – 3 a and 1 – 3 are rationalized in the context of quantum mechanical calculations.     

Simultaneous RP-HPTLC Method for Determination of Levodopa,Carbidopa, and Entacapone in Combined Tablet Dosage Form

JPC – Journal of Planar Chromatography – Modern TLC - A simple, rapid, specific, and accurate reverse-phase high-performance thin-layer chromatography (RP-HPTLC) method was developed...     

Simultaneous HPTLC Analysis of E-Guggulsterone,Z-Guggulsterone, 11-Keto-β-Boswellic Acid,and 3-Acetyl-11-Keto-β-Boswellic Acid in an Anti-Arthritic Formulation

JPC – Journal of Planar Chromatography – Modern TLC - A simple, precise, and rapid HPTLC method has been established for simultaneous analysis of E-guggulsterone, Z-guggulsterone,...     

A Novel Synthesis of 1-Aryl-9-alkyl-2, 3, 3a, 4, 9, 9a-hexahydro-1H-pyrrolo[2, 3-b] quinoxalines by lithium aluminium hydride reduction of N-phenyl-1-benzimidazolyl-succinimides

The N-substituted 1-benzimidazolyl-succinimides 6a – v (Scheme 1, Table 1 and 2) have been prepared by the reaction of benzimidazole and its derivatives with maleimides. Reduction of the N-cyclohexyl and N-cyclo-octyl substituted 1-benzimidazolyl-succinimides 6i – k with lithium aluminium hydride gives the normally expected substituted (N-alkyl-3-pyrrolidinyl)benzimidazoles 14i – k . However by LiAlH₄-reduction of the N-phenyl substituted 1-benzimidazolylsuccinimides 6a – h mainly the 1-aryl-9-alkyl-2, 3, 3a, 4, 9, 9a-hexahydro-1H-pyrrolo[2, 3-b]quinoxalines 7a – h are obtained. The mechanism of this unusual reduction has been elucidated.