共查询到20条相似文献,搜索用时 15 毫秒
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1 INTRODUCTION Pyridazinone derivatives represent one of the most active classes of compounds possessing a wide spectrum of biological activity. It was widely used in pharmaceuticals and agrochemicals[1, 2]. Rohm Haas Company had reported that pyridazinones exhibit useful plant growth regulating effects [3,4]. It was also reported that diacylhydrazines exhibit excellent insecticides [5~7]. In view of these facts, it was contemplated to synthesize compounds con- taining both pyridazinone … 相似文献
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The condensation reaction between 5-amino-4,6-dichloro-2-methylprimidine and 1-acetyl-2-imidazolin-2-one using POCl3 as solvent gave 4,6-dichloro-2-methyl-5-(1-acetyl-tetra-hydro-imidazo-2-ylidene)-aminopyrimidine predominantly and 4,6-dichloro-2-methyl-5-{1-1-(2-oxo-tetrahydro-imidazolyl)]-acetene}-aminopyrimidine as by-product. No 4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyrimidine was found. The result indicated an esterifi-cation-addition-elimination mechanism. 相似文献
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1 INTRODUCTIONCrownandazacrownetherhavebeenusedwidelyashostsforrecognizingguestmetalions.[1~ 4] Thiacrownethersincorporatingonlysulfuratomsinringalsohavebeenstudiedasextractingreagentsforsomesoftmetalions.[5] On lyfewstudiesonmixed donorcrownethercontain ing… 相似文献
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2 氨基 4 氯 5 甲基苯磺酸是合成染料和颜料的重要中间体 ,主要用于合成C .I.颜料红等[1] 。目前该产品的合成是以对硝基甲苯为原料 ,经氯化、还原、磺化而成[2 ] 。磺化过程需在压力容器中进行 ,存在成本高 ,溶剂及副产物二氯苯、多氯联苯有毒等问题[3,4] 。为此采用无毒、价廉的汽油和石油醚作为混合溶剂 ,常压下合成 2 氨基 4 氯 5 甲基苯磺酸是本工作的目的。1 实验部分1 .1 主要仪器和药品X4熔点测定仪 ,日本 2 6 0 5 0型红外光谱仪 ,日本LC 6A高效液相色谱仪 ,JEOLFX 90Q型核磁共振光谱仪 ,美国PE 2 4 0 0自动元… 相似文献
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Fe—Ce—N—O,Fe—Y—N—S溶液的热力学研究 总被引:1,自引:1,他引:0
本文主要研究了在1570~1650℃范围内Fe-Ce-N-O、Fe-Y-N-S溶液的热力学性质,得到主要结果如下:(1)铈、钇增加氮的溶解度,氧轻微地增加氮的溶解度,硫轻微地减少氮的溶解度;(2)铈、钇、氧、硫与氮的相互作用系数与温度的关系。e_N~(Ce)=(-6230/T) 2.670,e_N~Y=(-6640/T) 2.986,e_N~O=(-3497/T) 1.650,e_N~S=264/T-0.128;(3)铈、钇脱氮产物为CeN、YN;(4)铈、钇脱氮常数与温度的关系:1gK_(CeN)-(-20960/T) 7.972,1gK_(YN)=(-20440/T) 7.863。 相似文献
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1 INTRODUCTIONOrganophosphorus compounds are ubiquitous in nature and they have broad applications in the fields of agriculture and medicine. During the past two decades, (-ketophosphonates and their derivatives containing sulfur have attracted considerable attention because these compounds are endowed with special physical, chemical and pharmacological properties due to the proximity of the carbonyl and the phosphoryl groups[1~8]. In the study on new pharmacenticals and agrochemicals, th… 相似文献
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1 INTRODUCTIONPyridazinone derivatives represent one of the most active classes of compounds possessing a wide spectra of biological activity. They are widely used in pharmaceuticals and agrochemicals[1,2]. Rohm- Haas Company had reported that N-tert-butyl- dibenzoylhydrazine exhibits excellent insecti- cides[3, 4] and t-butyl plays an important role in the insecticide activity [5]. In the previous paper, we had reported that 1-aryl-1,4-dihydro-3- acylhydrazino- carbonyl-4-one-6-methylpy… 相似文献
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<正> C20H21NO3,Mr=323.39,monoclinic, space group P21, a= 7. 338(2), b=15. 419(3),c=7. 515(1)A,β=95.98(1)°,V= 845. 7(2)A3,Dm(flotation in aq. KL)=1.267,Dx(Z=2)=1.270gcm-3,λ(MoKα)=0.71069A,μ=0.08cm-1,F(000)=344,T=295°K,final RF=0. 042 for 1651 observed reflections. The title compound was synthesized and established as the trans isomer, with the phenyl and carbomethoxy substituents occupying pseudo-axial and axial positions, respectively, of the piperidin-2-one ring in a half-chair conformation. 相似文献
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Synthesis of 4-Amino-5-furyl-2-yl-4H-1, 2, 4-triazole-3-thiol Derivatives as a Novel Class of Endothelin(ET) Receptor Antagonists 总被引:1,自引:0,他引:1
XinYongLIU WenFangXU JingDeWU 《中国化学快报》2003,14(8):790-793
A series of novel 3-alkylthio-4-arylideneamino-5-(2-furyl)-l, 2, 4-triazole derivatives were synthesized. Their chemical structures were confirmed with elemental analysis and spectral data. Endothelin(ET) receptor competitive binding assay showed that some compounds exhibited high selective as potent ET-1 receptor antagonist. 相似文献
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