The Preparation, Characterization and X-ray Structural Analysis of Tetrakis[1-Methyl-3-(2-Propyl)-2(3H)-Imidazolethione]Cadmium(II) Hexafluorophosphate

Abstract  A new compound, [Cd(mipit)₄][PF₆]₂ has been synthesized and characterized via standard solid and solution state methods including single crystal X-ray crystallography (mipit = 1-methyl-3-(2-propyl)-2(3H)-imidazolethione). The title compound crystallizes in tetragonal space group I4 ₁ /a with a = 12.478(2) ?, b = 12.478(2) ?, c = 28.806(6) ?, and Z = 4. The complex is a high melting, colorless solid that has a distorted tetrahedral CdS₄ coordination geometry. Thermogravimetric analysis results for the title compound as well as for another potential CdS synthon and two potential CdSe synthons are reported. Graphical Abstract  The synthesis and characterization of the title compound, a new ionic homoleptic cadmium complex, tetrakis[1-methyl-3-(2-propyl)-2(3H)-imidazolethione]cadmium(II) hexafluorophosphate is reported. The results of a single crystal X-ray diffraction analysis reveal a distorted tetrahedral CdS₄ coordination sphere about the cadmium. Electronic supplementary material  The online version of this article (doi:) contains supplementary material, which is available to authorized users.     

The preparation, characterization, and X-ray structural analysis of dichlorobis[1-methyl-3-(2-propyl) -2(3H)-imidazolethione]mercury(II)

A new compound of mercury(II) chloride complexed to 1-methyl-3-(2-propyl) -2(3H)-imidazolethione (mipit) has been prepared and characterized via standard methods and X-ray crystallography. The structural significance of this study is that it shows one of the few monomeric examples of a mercury(II) chloride thione complex reported to date. The compound crystallizes in space group P2₁/c with a = 17.143(6) Å, b = 17.047(6) Å, c = 14.759(5) Å, = 105.899(5)°, V = 4148(2) ų, Z = 8. The coordination sphere is distorted tetrahedral with Hg–S bonds and Hg–Cl bond distances falling within the normally expected ranges. Bond angles ranged from 108.11(4)° to 115.51(4)° with the widest angle being observed for the S–Hg–S linkage. Ligand bond distances and angles including the C=S distance are within the normally expected values observed for this compound.     

Crystal structures of 3-[1-Benzenesulfonyl-3-phenylsulfanyl-1H-indol-2-yl]-1-[4-(methyl (I)/methoxy (II) phenyl)]-2-phenyl-propane-1-one

The compounds 3-(1-Benzenesulfonyl-3-phenylsulfanyl-1H-indol-2-yl)-1-[4-methyl (I)/methoxy (II)phenyl)]-2-phenyl-propane-1-one crystallize in triclinic space group P . The details are: compound I a = 11.941(6) ?, b = 12.154(7) ?, c = 13.006(7) ?, α = 63.124(8)°, β = 84.464(9)°, γ = 64.810(8)°, V = 1519.7(14) ?³, Z = 2, D _cal = 1.284 Mg m⁻³, and R = 0.0382 (wR = 0.0978); compound II a = 11.897(6) ?, b = 12.268(6) ?, c = 13.001(7) ?, α = 61.919(8)°, β = 83.480(8)°, γ = 64.676(7)°, V = 1504.0(14) ?³, Z = 2, D _cal = 1.333 Mg m⁻³, and R = 0.0422 (wR = 0.1049). The indole ring system in both the molecules I and II are not strictly planar and the dihedral angles formed by the pyrrole and benzo planes are 4.0(7)° and 3.5(8)°, respectively. The C–HO, C–Hπ and ππ types of interactions stabilize the molecules in the unit cell in addition to van der Waal's forces in I and II.     

Syntheses,characterization and crystal structures of two structurally similar Schiff bases isonicotinic acid [1-(3-methoxy-2-hydroxyphenyl)methylidene]hydrazide and isonicotinic acid [1-(4-dimethylaminophenyl)methylidene]hydrazide monohydrate

The Schiff base compounds, isonicotinic acid [1-(3-methoxy-2-hydroxyphenyl) methylidene]hydrazide (C₁₄H₁₃N₃O₃, 1) and isonicotinic acid [1-(4-dimethylaminophenyl) methylidene]hydrazide monohydrate (C₁₅H₁₆N₄O·H₂O, 2) have been synthesized by the condensation of equimolar 3-methoxysalicylaldehyde or 4-dimethylaminobenzaldehyde with isonicotinic acid hydrazide in MeOH or EtOH. The compounds were characterized by elemental analysis, IR, ¹HNMR spectra, and single crystal X-ray diffractions. Compound 1 crystallizes in the monoclinic space group P-1 with unit cell dimensions a = 7.662(1) ?, b = 16.249(2) , c = 10.874(2) ?, β = 110.426(3)°, V = 1268.7(3) ′³, Z = 4, R ₁ = 0.0644, and wR ₂ = 0.1283. Compound 2 crystallizes in the orthorhombic space group P2₁2₁2₁ with unit cell dimensions a = 7.388(1) ?, b = 11.812(1) ?, c = 17.197(2) ?, V = 1500.7(2) ′³, Z = 4, R ₁ = 0.0585, and wR ₂ = 0.1143. X-ray structure determinations revealed that the molecules of both compounds display trans configurations with respect to the C=N double bonds. In the crystal structure of 1, molecules are linked through N–H···N intermolecular hydrogen bonds, forming layers parallel to the bc plane, while in the crystal structure of 2, molecules are linked through N–H···O, O–H···O, and O–H···N intermolecular hydrogen bonds, forming a network. Supplementary material CCDC-615072 and 620235 contain the supplementary crystallographic data for this paper. These data can be obtained free of charge at http://www.ccdccam. ac.uk/const/retrieving.html or from the Cambridge Crystallographic Data Centre (CCDC), 12 Union Road, Cambridge CB2 1EZ, UK; fax: +44(0)1223–336033 or e-mail: deposit@ccdc.cam.ac.uk.     

Synthesis and Crystal Structure of Copper II and Silver I Complex with 1,4-diazabicyclo[2.2.2]octane[Cu(CBC)2(Dabco)(H2O)] n (1) and [Ag2(HBC)2(Dabco)] n (2)

Two 1D polymeric complex, [Cu(CBC)₂(Dabco)(H₂O)] _n (1) and [Ag₂(HBC)₂(Dabco)] _n (2) have been synthesized and characterized by X-ray single crystal analysis, where CBCH is p-chlorobenzoic acid, HBCH 2 is 2-hydroxybenzoic acid and Dabco is 1,4-diazabicyclo[2.2.2]octane. Complex 1 has been obtained in high yield by hydrothermal synthesis from CuO and CBCH and Dabco, and complex 2 has been obtain by evaporation of the solvent from silver salicylate and Dabco, 1 crystallizes in the orthorhombic space group Pmn2 ₁ with a = 24.3310(5) ?, b = 6.9050(6) ?, c = 5.9980(5) ?, Z = 2, V = 1007.70(4) ?³ and Dx = 1.657 g cm⁻³, 2 crystallizes in the monoclinic space group P2 ₁ /m with a = 10.292(3) ?, b = 6.913(2) ?, c = 14.417(4) ?, β = 95.660(5), Z = 2, V = 1020.8(5) ?³ and Dx = 1.959 g cm⁻³. The final R value is 0.0302 for 1323 measured reflections for 1 and the final R value is 0.0684 for 1545 measured reflections for 2. The atomic arrangement is built by infinite one-dimensional polymeric chain in both complexes. These chains are cross-linked by hydrogen bonds involving the coordinated water molecules to form a two-dimensional framework in complex 1.     

2-(1-Methyl-1H-indol-3-ylmethylene)-1-aza-bicyclo[2.2.2] octan-3-one: Acid-catalyzed isomerization of the Z isomer to the E isomer

Crystals of (Z)-2-(1-methyl-1H-indol-3-ylmethylene)-1-aza-bicyclo[2.2.2]octan-3-one (I) were obtained from a condensation reaction of 1-methyl-1H-indole-3-carboxaldehyde with 1-aza-bicyclo[2.2.2]octan-3-one and subsequent crystallization of the product from methanol. The isomeric (E)-2-(1-methyl-1H-indol-3-ylmethylene)-1-aza-bicyclo[2.2.2] octan-3-one hydrochloride (II) was obtained by treating a methanolic solution of I with a 1M solution of hydrogen chloride diethyl ether, followed by crystallization of resultant product from methanol. Crystal data: I, is monoclinic, P2₁, a = 5.7440(10), b = 11.102(2), c = 10.708(2) Å, = 91.751(10)°, and V = 682.5(2) ų with Z = 2, for D _cal= 1.296 mg/m³ and II, is monoclinic, P2₁/c, a = 8.8510(2), b = 17.4990(5), c = 20.4300(5) Å, = 101.3620(12)°, V = 3102.26(14) with Z = 8, for D _cal= 1.316 mg/m³.     

Crystal structure of potassium tris[3-(2-pyridyl)pyrazolyl]hydroborate

The crystal structure of the potassium tris[3-(2-pyridyl)pyrazolyl]hydroborate has been determined. Potassium tris[3-(2-pyridyl)pyrazolyl]hydroborate crystallizes in the orthorhombic space group Pca2₁ with the parameters a=30.7323(5) ?, b=8.3083(1) ? and c=9.2173(2) ?, V=2353.48(7) ?³ with Z=4. The crystal structure reveals the formation of continuous chains where two bidentate arms of the hydroborate ligand are coordinated to one potassium and the third to another cation. The structures of numerous transition metal and actinide salts have been reported during the last decades but no alkali metal complexes were available.     

1-[2-(p-Tolyl)-1-diazenyl]-3-({3-[2-(p-tolyl)-1-diazenyl] perhydrobenzo[d]imidazol-1-yl}methyl)perhydrobenzo[d]imidazole: synthesis,characterization and X-ray crystal structure

1-[2-(p-Tolyl)-1-diazenyl]-3-({3-[2-(p-tolyl)-1-diazenyl]perhydrobenzo[d]imidazol-1-yl}methyl)perhydrobenzo[d]imidazole(1) has been synthesized by reactionof a mixture of 1,2-diaminocyclohexane and formaldehyde withp-toluene diazonium chloride inaqueous solution. The product has been characterized by IR and NMRspectroscopy and elemental analysis. A crystal grown from solution ina mixed solvent system of ethyl acetate and hexanes was analyzed byX-ray crystallography. The solution of the crystal structure of(1) is important in establishing theconnectivity of this molecule and other compounds of similarstructure. The crystal structure of (1) is compared with the previously reportedstructure of the p-cyano analogue(2). Compounds (1) and (2)differ principally in the relative orientation of the heterocyclicrings; in (1), the molecule has adistinct V-shape, whereas compound (2) adopts a more extended conformation.Significant conjugation within the triazene moieties is evident inboth (1) and (2), as manifested in the N465=N andN–N bond lengths. The conjugation is greater in (2) due to the extended conjugation through tothe nitrile group. The title compound (1){C₂₉H₄₀N₈}crystallizes in the monoclinic, space group C2/c, with lattice constants: a = 30.532(6) ?,b =5.9050(12) ?, c= 15.463(3) ?, α = 90°,β = 99.94(3)°, γ = 90°,V =2746.0(10) ?³, Z = 4, D _c =1.209 mg m⁻³,F(000) = 1076, R ₁ = 0.0785,wR ₂= 0.1877.     

The Preparation,Characterization and X-ray Structural Analysis of Tetrakis[1,3-dimethyl-2(3H)-imidazoleselone]cadmium(II) Hexafluorophosphate

Abstract A new compound, [Cd(dmise)₄][PF₆]₂, has been synthesized and characterized via standard solid and solution state methods including single crystal X-ray crystallography (dmise = 1,3-dimethyl-2(3H)-imidazoleselone). The title compounds crystallizes in orthorhombic space group P bcn with a = 12.783(3), b = 22.206(4), c = 13.153(3) ?, V = 3733.8(13) ?³, Z = 4. The complex is a high melting, yellow water soluble 2:1 electrolyte solid that state has a flattened tetrahedral CdSe₄ coordination geometry. To date this is the only structural study reported for a homoleptic selenourea complex of cadmium. Graphical abstract The Preparation, characterization and X-ray structural analysis of Tetrakis[1,3-dimethyl-2(3H)-imidazoleselone]cadmium(II) hexafluorophosphate Daniel J. Williams, Bradley J. McKinney, Ben Baker, Kevin P. Gwaltney and Donald VanDerveer Tetrakis[1,3-dimethyl-2(3H)-imidazoleselone][PF₆]₂ is prepared in 82% yield by direct combination of cadmium acetate dihydrate, ammonium hexafluorophosphate, and the ligand in boiling acetonitrile. X-ray crystallography shows a structure with a distorted tetrahedral coordination sphere around the cadmium. This is the first report of a structural characterization of a homoleptic cadmium selenourea complex. Electronic supplementary material The online version of this article (doi: ) contains supplementary material, which is available to authorized users.     

Interaction of N-(4-methoxyphenyl)-2,4,6-trinitroaniline with tris(triphenylphosphinegold)oxonium tetrafluoroborate; X-ray structure of salt [O(AuPPh3)3]2 2{(4-MeO)C6H4-N-C6H2-[2,4,6-(NO2)3]}

The structure of the auration product of N-(5-methoxybenzene)-2,4,6-trinitroaniline is determined. The compound of composition C₆₇H₅₄Au₃N₄O₈P₃ (3) crystallizes in triclinic space group P with a = 13.8280(4), b = 14.7641(4), c = 17.4531(5) Å, α = 111.550(1), β = 102.779(1), γ = 103.040(1)^∘, Z = 2. The compound represents a salt tris(triphenylphosphinegold) oxonium N-(4-methoxyphenyl)-2,4,6-trinitroanilinate, with a hexanuclear dimeric structure of the cation and a para-quinoid form of the anion that is responsible for the dark-red color of the compound.     

Two concomitant polymorphs of 3,3′,4,4′-tetrakis(phenylethynyl)-1,1′-[2,2,2,-trifluoro- 1-(trifluromethyl)ethanediyl]bisbenzene

A representative compound of bis-ortho-diynyl arene (BODA), with a general formula [(m,p)R₂–Ph]₂ –X, where R: –C≡C–Ph and X: >C(CF₃)₂ has been structurally characterized. The compound is being investigated as a monomer for high-performance polyarylene networks and glassy carbon precursors. The bis(trifluoromethyl) derivative crystallizes in two concomitant polymorphic forms. The two polymorphs form a monotropic system with melting points of 436 and 463 K. The metastable form yields monoclinic crystals (P2₁/n, Z=4). a=12.677(3) ?, b=11.677(2) ?, c=24.026(5) ?, β=93.79(3)°. The thermodynamically stable form is monoclinic as well (P2₁/c, Z=8), a=10.7983(6) ?, b=30.628(2) ?, c=21.648(1) ?, β=94.737(1)° with small voids indicating less efficient packing. The two polymorphs contain different conformers of the rotationally flexible molecule.     

Synthesis,Crystal Structure and DNA Binding Property of Diaquadi(4-methylbenzoyloxy)bis[2-(4-pyridyl)-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide]cobalt(II)

Abstract  

A novel cobalt(II) complex of [Co(4-MePhCOO)₂(NITpPy)₂(H₂O)₂] (1), where NITpPy is short for 2-(4-pyridyl)-4,4,5,5-tetramethylimidazoline-1-oxy 3-oxide(C₁₂H₁₆N₃O₂), was synthesized and structurally characterized by X-ray diffraction analysis. The X-ray diffraction analysis reveals that 1 crystallizes in the triclinic space group P-1 with a = 6.7910(10) ?, b = 12.4421(15) ?, c = 12.9169(16) ?, α = 89.8470(10)°, β = 89.8480(10)°, γ = 76.991(2)°, and Z = 1. The Co atom in the complex is located on the center of inversion and lies in a distorted octahedral geometry defined by an N₂O₄ donor set. The interaction of 1 with calf thymus DNA (CT-DNA) was investigated by UV–vis absorption and emission spectroscopy, which indicating that 1 could bind to DNA through electrostatic interaction.     

Synthesis, characterization, and structural analysis of ethyl (2Z)-3-(4-chlorophenyl)-2-cyano-3-(methoxyamino)prop-2-enoate

Ethyl (2Z)-3-(4-chlorophenyl)-2-cyano-3-(methoxyamino)prop-2-enoate was prepared by reacting the lithium salt of ethyl cyanoacetate with (Z)-O-methyl-4-chloroben-zohydroximoyl fluoride. This compound crystallizes in space group Pbca,with lattice constants a=7.5740(15) ?, b=11.337(2) ?, and c=30.424(5) ? at 110 K. Characterizations include spectrometric identifications employing IR, UV, and ¹H and ¹³C NMR. The compound exists in the solid as the enamine tautomer, with the cyano group cis to the 4-chlorophenyl group (the Z configuration). The C=C and C–N bond distances are 1.3930(16) ? and 1.3278(16) ?, respectively. The N–H group forms a bifurcated hydrogen bond with acceptors C=O (intramolecular) and C≡N (intermolecular).Supplementary material CCDC-289444 contains the supplementary crystallographic data for this paper. These data can be obtained free of charge via www.ccdc.cam.ac.uk/data_request/cif, by e-mailing data_request@ccdc.cam.ac.uk, or by contacting The Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge CB2 1EZ, UK; Fax: +44(0)1223-336033.     

Synthesis and structure of tris[2-(1-naphthalenyloxy)ethyl]amine and tris[2-(1-naphthalenyloxy)ethyl]amine perchlorate

Syntheses and crystal structures of tris[2-(1-naphthalenyloxy)ethyl]amine 1 and tris[2-(1-naphthalenyloxyl)ethyl]amine perchlorate 2 are reported. Compound 1 crystallizes in the rhombohedral system, space group R3¯ with a = 13.077(4), c = 29.011(8) Å, and D _calc = 1.233g/cm³ for Z = 6; compound 2 crystallizes in the cubic system, space group P2₁3 with lattice parameters a = 14.630(5) Å and D _calc = 1.332g/cm³ for Z = 4. In 1, three naphthalene rings make dihedral angles of 109.21, 70.78, 70.78,° respectively. In 2 they make dihedral angles of 107.3, 72.7, 72.7° respectively. Deviation of N from the plane (C(12),C(12)i,C(12)ii) in 1 is 0.3742 Å which is less than that in (2) (–0.4223 Å). The crystals structure is stabilized by van der Waals interactions in both compounds.     

Structure of 4-(2-chloro-4,5-dimethoxybenzylidene)-2-methyl-5-oxazolone. X-ray and NMR study

The azlactone of 6-chloroveratraldehyde 3 (4-(2-chloro-4,5-dimethoxybenzylidene)-2-methyl-5-oxazolone) was synthesized from 6-chloroveratraldehyde 2 and its structure investigated using X-ray crystallographic and nuclear magnetic resonance methods. Compound 3 crystallized in the P2₁/c (#14) space group (Z = 4) with cell dimensions a = 9.148(2), b = 22.938(2), c = 6.707(1) Å, and = 111.50(2)°. The X-ray study shows that azlactone 3 exists as the Z-isomer and crystallizes as a planar structure, i.e., both the phenyl and azlactone ring systems, as well as the functional groups attached to them, lie in the same plane. The ¹H and ¹³C NMR spectral values also support the formation of the Z-isomer only, during the synthesis of 4-(2-chloro-4,5-dimethoxybenzylidene)-2-methyl-5-oxazolone.     

Crystal and molecular structure of bis(8-phenylmenthyl) 2-(2-methyl-5-oxo-3-cyclohexen-1-yl)propandioate, C42H54O5· CH3CN

The X-ray crystal structure of the title compound, as crystallized from acetonitrile-water was determined. The relative stereochemistry of the cyclohexenone ring with respect to the 8-phenylmenthyl esters was determined. The title compound crystallizes in the noncentrosymmetric space group P2₁, with a=8.9850(10) ?, b=15.575(3) ?, c=14.478(2) ?, β=94.61(2)°, and D _calc=1.118 g cm⁻³ for Z=2.     

Synthesis and crystal structures of the bis-Schiff bases of 2-(methylthio)aniline with isophthaldehyde, terephthaldehyde, and para-diacetylbenzene

The crystal structures of the new compounds 1,3-bis(((2-methylthio)phenylimino)methyl)benzene (1), 1,4-bis(((2-methylthio)phenylimino)methyl)benzene (2), and 1,4-bis(1-((2-methylthio)phenylimino)ethyl)benzene (3) were obtained by single crystal X-ray diffraction. Compound 1 crystallizes in the orthorhombic space group Pna2₁ with a=16.8250(13) ?, b=18.1068(13) ?, c=6.3086(5) ?; and Z=4. Compound 2 crystallizes in the triclinic space group with a=6.7532(7) ?, b=9.4433(9) ?, c=15.2473(15) ?; and α=86.339(2)°, β=80.609(2)°, γ=80.962(2)°; and Z=2. Compound 3 crystallizes in the triclinic space group with a=6.787(3) ?, b=7.517(3) ?, c=10.653(4) ?; and α=89.998(7)°, β=72.341(7)°, γ=75.998(7)°; and Z=1. Details of the synthesis, structures, and spectroscopic results are discussed.     

Synthesis and crystal structures of 2-amino-3-cyano-4-(2-chlorophenyl)-1,4-dihydro-2H-pyrano[3, 2-h]quinoline and 2-amino-3-cyano-4-(2-chlorophenyl)-8-(2-chlorobenzylidene)-1,4,5,6,7,8-hexahydrobenzo[b]pyran

The title compounds 2-amino-3-cyano-4-(2-chlorophenyl)-1,4-dihydro-2H-pyrano[3, 2-h]quinoline 1 (C₁₉H₁₂ClN₃O, M _r = 333.77) and 2-amino-3-cyano-4-(2-chlorophenyl)-8-(2-chlorobenzylidene)-1,4,5,6,7,8-hexahydrobenzo[b]pyran 2 were synthesized and crystallized. The crystals of compound 1 are triclinic, space group P-1, a = 7.488(2), b = 9.127(3), c = 12.252(3) Å, = 73.58(2), = 78.38(2)°, = 75.39(2), Z = 2, V = 769.5(4) ų; The compound 2 crystallizes in space group P2₁/n, with cell parameters a = 13.582(2), b = 8.974(1), c = 16.960(2) Å, = 103.34(1)° and D _calc = 1.352 g/cm^–3 for Z = 4. X-ray analysis reveals that atoms C(1)—C(5) and O form a pyran ring in compound 1, which adopts half-chair conformation. In compound 2 the atoms C(12)—C(16) and O form a pyran ring which adopts boat conformation, another six-membered ring (C(8)—C(13)) adopts a half-chair conformation. In addition, there are intermolecular hydrogen bonds in the crystal structures 1 and 2.     

Crystal structure oftrans-tetrachlorobis[2-(2-1H-imidazolyl)-1H-imidazolium]cadmium(II), [Cd(H3biim)2Cl4]

The reaction between cadmium(II) chloride and 2,2'-bi-1H-imidazole (H₂biim) in an acidic solution affords [Cd(H₃biim)₂Cl₄] (H₃biim=2-(2-1H-imidazolyl)-1H-imidazolium) in 63% yield. The compound crystallizes in the triclinic space groupP1, wherea=8.072(2),b=8.100(2),c=8.593(2) Å, =75.89(2), =62.94(2), =63.29(1)°,V=446.4(2) ų, andZ=1. The central Cd atom exhibits an octahedral geometry composed of a Cl₄N₂ core. The Cd-N bond distance is 2.392(2) Å. Cd–Cl distances are 2.5919(9) and 2.671(1) Å.     

Inclusion property of (R,R)-(-)-trans-2,3,-bis(hydroxydiphenylmethyl)-1,4-dioxaspiro[4,4]nonane for aromatic components

An optically active host molecule, (R,R)-(-)-trans-2,3-bis(hydroxydiphenylmethyl)-1,4- dioxaspiro[4,4]nonane (1), is able to form inclusion complexes with nonpolar aromatic components such as benzene, toluene, p-xylene, mesitylene, and ethylbenzene. The host 1 crystallizes in the monoclinic space group C2 with a = 15.694(2), b = 9.326(2), c = 18.457(1) Å, = 10.34(1)°, and Z = 4. An inclusion complex (1-B) of 1 with benzene crystallizes in the orthorhombic space group P2₁2₁2 with a = 17.007(4), b = 19.670(5), c = 8.634(4) Å, and Z = 4. An inclusion complex (1-X) involving both 1 and p-xylene has the monoclinic space group P2₁ with a = 17.211(3), b = 20.143(3), c = 8.603(3) Å, = 92.64(2)°, and Z = 2. In the inclusion complexes, molecules of 1 are dimerized by intramolecular and intermolecular hydrogen bonds forming eight-membered (OH)₄ rings. The benzene and p-xylene molecules fit into the voids of the crystal packing of 1. In addition, the inclusion complexes are stabilized by van der Waals contacts between the hydrophobic sites. Thermal analysis of the inclusion complexes indicated that the number and the size of the alkyl group of the aromatic components affects the stability of the inclusion complexes.