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1.
I. V. Ukrainets P. A. Bezuglyi V. I. Treskaya A. V. Turov S. V. Slobodzyan O. V. Gorokhova 《Chemistry of Heterocyclic Compounds》1991,27(8):907-909
3-Amino-2-carboxymethylquinazolin-4(3H)-one was obtained by hydrazinolysis of 2-carbethoxymethyl-4H-3,1-benzoxazin-4-one. Its transformations into 2-hydroxypyrazolo[5,1-b]quinazolin-9(1H)-oneand3-amino-2-hydrazido-(orbenzylamido)carbonylmethylquinazoline-4(3H)-ones were studied.For Communication 1, see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1128–1130, August, 1991. 相似文献
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I. V. Ukrainets S. G. Taran O. A. Evtifeva O. V. Gorokhova N. I. Filimonova A. V. Turov 《Chemistry of Heterocyclic Compounds》1995,31(2):176-179
The bromination of 3-alkyl- and 3-ethoxycarbonyl-2-oxo-4-hydroxyquinolones by molecular bromine gave 3-bromo-3-R-2,4-dioxoquinolones. Under analogues conditions, 1-R-2,4-dioxo-3H-quinolone-3-carboxylic acids form 1-R-3-bromo-2-oxo-4-hydroxyquinolones. The results of the study of the antimicrobial activity of the compounds synthesized are presented.For Communication 25, cf. [1].Ukrainian Pharmaceutical Academy, Khar'kov, 310002. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 204–207, February, 1995. Original article submitted November 8, 1994. 相似文献
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I. V. Ukrainets S. G. Taran O. V. Gorokhova P. A. Bezuglyi A. V. Turov 《Chemistry of Heterocyclic Compounds》1994,30(2):204-207
In a solution of DMF, 2-carbethoxymethyl-4H-3,1-benzoxazin-4-one reacts with primarily aromatic amines basically with the formation of the corresponding 2-carbethoxymetlzyl-3-arylquinazolin-4(3H)-ones. Possible mechanisms of these chemical transformations are reported and discussed.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 225–228, February, 1994. Original article submitted June 28, 1993. 相似文献
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P. A. Bezuglyi I. V. Ukrainets V. I. Treskach A. V. Turov 《Chemistry of Heterocyclic Compounds》1992,28(4):438-439
Acylation of methyl N-methylanthranilate with phenylacetyl chloride with subsequent intramolecular cyclization of the resulting anilide was used to synthesize 1-methyl-3-phenyl-4-hydroxy-2-quinolone (arboricine).See [1] for Communication 1.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 522–524, April, 1992. 相似文献
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V. G. Poludnenko O. B. Didinskaya A. F. Pozharskii 《Chemistry of Heterocyclic Compounds》1986,22(7):783-785
The reaction of 1,8-naphthylenediamine with perfluoropolyoxaalkanoyl fluorides and -fluorosulfonylperfluropolyoxaalkanoyl fluorides yielded 2-perfluoropolyoxaalkyl-substituted perimidines. Their basicity and sulfonation by sulfuric acid were studied.For communication 3, see [1].Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 973–975, July, 1986. 相似文献
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I. V. Ukrainets L. V. Sidorenko O. V. Gorokhova S. V. Slobodzyan 《Chemistry of Heterocyclic Compounds》2007,43(1):63-66
The reaction of 2-ethoxycarbonylmethyl-4H-3,1-benzoxazin-4-one with malononitrile in dry pyridine leads to 1-hydroxy-3,6-dioxo-4,6-dihydro-3H-pyrimido[1,2-a]quinoline-5-carbonitrile.
Acetoacetic and cyanoacetic esters under analogous conditions form anilides of 4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic
acid while diethyl malonate gives N,N′-di-2-carboxyanilides of malonic acid.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 1, pp. 75–79, January, 2007. 相似文献
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2-Polyfluoroalkylchromones. 6. Synthesis of substituted 2-morpholino-2-trifluoromethylchroman-4-ones
Morpholine adds smoothly at the double bond of substituted 5- and 8-nitro-2-trifluoromethylchromones to form the corresponding 2-morpholino-2-trifluoromethylchroman-4-ones. 6-Methoxy-5-nitro-2-trifluoromethylchromone adds also benzylamine, whereas 7-methoxy-8-nitro-2-trifluoromethylchromone undergoes ring opening under the action of benzylamine to give 3-benzylamino-4,4,4-trifluoro-1-(2-hydroxy-4-methoxy-3-nitrophenyl)but-2-en-1-one. 相似文献
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M. Kh. Mamarakhmonov M. A. Ashirmatov Kh. M. Shakhidoyatov 《Chemistry of Heterocyclic Compounds》2001,37(8):993-996
Semiempirical quantum-chemical calculations have been carried out of the molecules of 2-oxopyrimidinones-4. The geometry and electronic structures and the stabilities of the tautomeric forms have been analyzed. 相似文献
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P. A. Bezuglyi I. V. Ukrainets V. I. Treskach A. V. Turov 《Chemistry of Heterocyclic Compounds》1991,27(11):1237-1238
3-Alkyl-4-hydroxy-2-quinolones were obtained in high yields via the Dieckmann intramolecular condensation of substituted malonic acid ethyl ester 2-carbalkoxyanilides.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 11, pp. 1533–1534, November, 1991. 相似文献
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Summary Electron paramagnetic resonance (e.p.r.) and optical absorption measurements were performed on K2SO4
− Na2SO4-ZnSO4 glasses containing 1–10 mol % of MnSO4·H2O. The spectra of Mn2+-doped samples exhibit a sextet centred at g = 2.03. The e.p.r. signal clearly shows its dependence on the dopant ion concentration. The optical absorption spectrum at
room temperature shows bands characteristic of Mn2+ ions in octahedral symmetry. The crystal field (Dq) and the Racah interelectronic repulsion (B and C) parameters have been evaluated. E.p.r. and optical absorption studies reveal that the Mn2+ ions go substitutionally to Zn ion sites and the site symmetry around the transition metal ion is octahedral. 相似文献
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I. V. Ukrainets S. G. Taran L. V. Sidorenko O. V. Gorokhova A. A. Ogirenko A. V. Turov N. I. Filimonova 《Chemistry of Heterocyclic Compounds》1996,32(8):960-970
Abstarct An alternative method has been developed for preparing and studying the antioxidant activity of 3-acylamino-2-oxo-4-hydroxyquinolones. Results are presented from an investigation of the antithyroid and antimicrobial action of the intermediate 2-oxo-3-(1 pyridinio)quinotin-4-olates and the 3-amino-2-oxo-4-hydroxyquinolines.For communication 30, see [1].Ukrainian Pharmaceutical Academy, Khar'kov 310002. Translated from Khimiya Geterotsklicheskikh Soedinenii, No. 8, pp. 1113–1123, August, 1996. Original article submitted June 10, 1996. 相似文献
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B. M. Bolotin L. S. Zeryukina R. V. Poponova N. I. Chernova R. u. Safina A. A. Fomichev 《Chemistry of Heterocyclic Compounds》1977,13(12):1291-1292
The reduction of 2-(2-tosylaminophenyl-4H-3,1-benzoxazin-4-one with zinc dust in acetic acid gives N-(o-tosylaminobenzyl)anthranilic acid, the structure of which was proved by mass spectrometry and the 13C NMR spectra.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 12, pp. 1619–1621, December, 1977. 相似文献
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Methyl 2-allyl-3-oxo-2,3-dihydrothiophene-2-carboxylate ( 2 ) photocyclizes selectively to methyl 2-oxo-7-thiatricyclo[3.2.1.03,6]octane-1-carboxylate ( 4 ). In contrast, 4-thia-2-cyclohexenone 3 , on irradiation, affords only low yields of dimers, cycloadducts (2-methylpropene) or RH reduction products (i-ProH). 相似文献
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K. Gewald U. Hain R. Schindler M. Gruner 《Monatshefte für Chemie / Chemical Monthly》1994,125(10):1129-1143
Summary 6-Amino-thiazolo[4,5-c]isothiazole derivatives4 are obtained by addition of hydrogen sulfide to the 4-Amino-thiazoline-5-carbonitrile2 followed by cyclooxidation of the intermediate thioamides3. In the presence of sodium sulfite the hydrolysis of the4-amino-2-methylthio-thiazolium salts5 derived from the title compounds1 yields the4-amino-thiazolin-2-ones6. By their further hydrolysis the 2,4-dioxo-thiazolidin-5-carboxamides8 are formed. The 2-oxo-and 2-thioxo-thiazolo [4,5-d]pyrimidin-7-ones and -thiones available from1 undergo ring opening by hydrolysis to give the substituted 4-amino-6-oxo- and 4-amino-6-thioxo-pyrimidine-5-thiols15a–h and13i–e. They have been isolated as their disulfides14 or 5-alkyl derivativesi.e. the substituted 4-amino-5-alkylthiopyrimidin-6-ones and -thiones16. In analogy, the intermediate 6-amino-7-oxo-thiazolo[4,5-d] pyrimidin-2-thione18 and the 7-amino-thiazolo[4,5-d]-pyrimidin-2-thione24 derived from1 react by ring cleveage to yield the 1,4-and 4,6-diamino-pyrimidin-5-thiole derivatives22 and27, respectively, isolated as their disulfides or alkylthio-derivatives. From the pyrimidine16b the pyrimido[5,4-b]1,4-thiazine derivative18 can be obtained. 相似文献
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I. V. Ukrainets L. V. Sidorenko O. V. Gorokhova N. L. Bereznyakova S. V. Shishkina 《Chemistry of Heterocyclic Compounds》2006,42(10):1296-1300
The alkylation of the ethyl esters of 4-methyl, 4-chloro-, and 4-amino substituted 2-oxo-1,2-dihydroquinoline-3-carboxylic
acid by ethyl iodide in the system DMF/K2CO3 has been studied. Features of the structure of the starting compounds and their effect on the ratio of the N-and O-alkyl
products formed are discussed.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1502–1507, October, 2006. 相似文献