共查询到20条相似文献,搜索用时 31 毫秒
1.
Javad Azizian Ali A. Mohammadi M. Kohshari Ali R. Karimi Mohammad R. Mohammadizadeh 《Journal of heterocyclic chemistry》2007,44(2):455-458
In the context of our high‐throughput organic synthesis program, we have studied the reactivity of special β‐keto esters toward the Biginelli reaction. We have found that a diethyl‐3‐oxoglutarate reacts with one molecule of urea and one molecule of aldehyde under solvent‐free conditions to give a new family of 3,4‐dihydropyrimidin‐2(1H)‐ones in good yields. 相似文献
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Osman M. E. El‐Dusouqui Nouria A. Al‐Awadi Mohamed H. Elnagdi Mervat M. Abdelkhalik 《Journal of heterocyclic chemistry》2008,45(6):1751-1753
1,2,3‐Triazolylpropanone was prepared and coupled with aryldiazonium salts yielding the corresponding arylhydrazones. Gas‐phase pyrolysis of the hydrazono derivative produced N‐arylamino‐2‐acetylimidazole as well as 2‐acetylimidazole. The latter is the product of further pyrolysis of the former. 相似文献
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Łukasz Groś Aneta Wesołowska Sławomir Westerlich Tadeusz Jagodziński 《Journal of heterocyclic chemistry》2007,44(1):167-176
The reaction of isothiocyanates with in situ generated carbanions of α,β‐unsaturated ketones yielded α,β‐unsaturated keto thioamides which in the reaction with acids or bases cyclized to give 2,6‐disubstituted thiopyran‐4‐ones and in the reaction with α‐bromoesters gave thiazolidin‐4‐one derivatives. The thiopyran‐4‐ones reacted with α,β‐unsaturated aldehydes to yield tetrahydrothiopyran[2,3‐b]pyridin‐4‐ones, while thioanilides were formed in the reaction with phenyl isothiocyanate. 相似文献
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Nicholas A. Jones James W. Antoon Alfred L. Bowie Jr. J. Brian Borak Erland P. Stevens 《Journal of heterocyclic chemistry》2007,44(2):363-367
2,2′‐Bipyridyl‐type compounds may be prepared by Suzuki‐Miyaura coupling of a 2‐pyridylboronic ester with 2‐haloazines and ‐azoles. Ten examples are presented with yields of 47 to 84%. Both arylbromides and arylchlorides undergo the coupling, but the reaction is sensitive to ring substitution adjacent to the halogen. 相似文献
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An efficient method for the synthesis of novel macrocyclic bis‐ethers from alizarin and also some new spiro ethers from various substituted ketones by the use of Barbier and ring‐closing metathesis (RCM) reactions has been developed. 相似文献
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Changsheng Yao Song Lei Cuihua Wang Chenxia Yu Shujiang Tu 《Journal of heterocyclic chemistry》2008,45(6):1609-1613
The solvent‐free synthesis of 5‐methyl‐7‐aryl‐4,7‐dihydrotetrazolo[1,5‐a]pyrimidine‐6‐carboxylic esters was performed and effectively catalyzed by sulfamic acid. Compared with conventional methods, this protocol features mild reaction conditions and high yields. Furthermore, it is solvent‐free and thus eco‐friendly. 相似文献
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A simple synthesis of several methyl 2‐oxo‐2,3‐dihydrobenzo[b]oxepine‐4‐carboxylates from Baylis‐Hillman adducts of O‐benzyl protected 2‐hydroxybenzadehydes has been described through the acetylation, cyanation, debenzylation, as well as acid assisted Pinner cyclization. 相似文献
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Yasser M. Loksha Erik B. Pedersen Paolo La Colla Roberta Loddo 《Journal of heterocyclic chemistry》2007,44(6):1351-1356
Different analogues of TMC120 derived from pyridazin‐3(2H)‐one rings were synthesized by coupling of 3,6‐dichloropyridazine with arylacetonitriles, phenols and/or aniline derivative followed by hydrolysis and alkylation with different benzyl bromide derivatives. 相似文献
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Kevin A. Memoli 《Journal of heterocyclic chemistry》2007,44(4):927-928
A novel pyrrolopyridodiazepine ring system was synthesized from methyl 2‐methyl nicotinate. 相似文献
14.
Abbas Shafiee Mohammad Z. Kassaee Ahamad R. Bekhradnia 《Journal of heterocyclic chemistry》2007,44(2):471-474
The synthesis of a series of novel 3,4‐diaryl‐1H‐pyrroles and related arylalkenes from p‐bromo thiophenol, tosylmethyl isocyanide and commercially available materials is reported. Arylalkenes having electron‐withdrawing substituents gave higher yield of 3,4‐diaryl‐1H‐pyrroles. 相似文献
15.
Daqing Shi Shunjun Ji Lihui Niu Jingwen Shi Xiangshan Wang 《Journal of heterocyclic chemistry》2007,44(5):1083-1090
A short and facile synthesis of pyrido[2,3‐d]pyrimidine derivatives was accomplished in good yields via the three‐component reaction of aldehydes, alkyl nitriles and aminopyrimidines in water in the presence of triethylbenzylammonium chloride (TEBAC). The structures of these compounds were characterized by elemental analysis, IR and 1H NMR spectra and further confirmed by single crystal X‐ray diffraction analysis. 相似文献
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A series of new unsymmetrical 3‐phenyl‐6‐benzyl‐1,2,4,5‐tetrazine derivatives 10a‐i were synthesized and characterized by IR, NMR, MS, and element analysis. The structures of 4a, 10c, 10d and 10h were analyzed by X‐ray crystallography, which had intermolecular C‐H‐N, C‐H‐Cl, C‐H‐II and II‐II interactions. 相似文献
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Shujiang Tu Qian Wang Yan Zhang Jianing Xu Jinpeng Zhang Xiaotong Zhu Feng Shi 《Journal of heterocyclic chemistry》2007,44(4):811-814
A series of new and significative bifunctional compounds containing two pyrazolo[3,4‐b]pyridine moieties has been synthesized through a rapid one‐pot three‐component reaction of dialdehyde, 5‐amino‐3‐methyl‐1‐phenylpyrazole and active methylene compounds in glycol under microwave irradiation without catalyst. The method has the advantages of good yield (85‐98%), short route and reaction time (45‐300s), wide reaction scope and easy work‐up procedure. 相似文献
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ortho‐Hydroxy acetyl benzofuran derivatives have been synthesized in a regioselective cyclodehydration of aryloxyketones obtained from β‐resacetophenone and α‐halo ketones. 相似文献
19.
Xue‐Yi Chen Charles Barnes Dr. Jerry R. Dias Prof. T. C. Sandreczki Prof. 《Chemistry (Weinheim an der Bergstrasse, Germany)》2009,15(9):2041-2044
Triethylamine hydroiodide crystals were formed during Sonogashira reactions; after complete reaction the solution retains a characteristic light color (see picture). Very sluggish Sonogashira reactions of electron‐enriched aryl diiodides have been carried out in high yield in an oxygen‐free, two‐chamber reaction system. The formation of triethylamine hydroiodide crystals was monitored to determine the completion of reaction.
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Venkatapuram Padmavathi Konda Mahesh Pinnu Thriveni Tippireddy Venkata Ramana Reddy 《Journal of heterocyclic chemistry》2007,44(5):1165-1169
A new class of 1,2,3‐selena/thiadiazoles and 2H‐diazaphospholes were synthesized by exploiting α‐ketomethylene group in phenacylsulfonylacetic acid methyl ester. 相似文献