| Inverse Optimizing Method of Bio-Temperature-Field Reconstruction in rf-Capacitive Hyperthermia |
| |
| 作者姓名： | 万柏坤 朱欣 程晓曼 林世寅 |
| |
| 作者单位： | [1]DepartmentofBiomedicalEngineeringandScientificInstrument,TianjinUniversity,Tianjin300072 [2]DeparmentofOptoelectronicInformationandElectronicEngineering,TianjinInstituteofTechnology,Tianjin300191 [3]DivisionofRadio-Physics,TianjinCancerInstituteandHospital,Tianjin300060 |
| |
| 摘 要： | We propose an inverse optimizing method, used in rf-capacitive hyperthermia to obtain a certain target tumour temperature and to avoid the over-heating of normal tissues. Based on the finite-element-method solutions of the Laplace electric potential equation and Penne‘s bio-heat transfer equation, the heating conditions are modified by the genetic algorithms recursively to minimize the objective function for searching an optimum physical configuration. With a simplified human tissue model extracted from an x-ray computed tomography slice which has deep- and shallow-seated turnouts, satisfactory simulation results are obtained both on bi-plate and three-plate systems, e.g. The tumour temperature is higher than 43℃ and the temperature of normal tissues is lower than 39℃. It is suggested that the proposed algorithm is snitable for both shallow and deep seated cancer oncology.
|
| 关 键 词： | 反转优化理论 高温 癌症 肿瘤学 肿瘤温度 X射线观测 生物温度场重建 |
| 本文献已被 维普 等数据库收录！ |
|
