| Monte Carlo Simulation on Coordinated Movement of Kinesin and Dynein Motors |
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| 作者姓名： | 王宏 窦硕星 王鹏业 |
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| 作者单位： | Laboratory of Soft Matter Physics, Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080 |
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| 基金项目： | Supported by the National Natural Science Foundation of China under Grant Nos 10334100 and 10674173. |
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| 摘 要： | Kinesin and dynein are two important classes of molecular motors which are responsible for active organelle trafficking and cell division. They can work together to carry a cargo, moving along the microtubule in a coordinated way. We use Monte Carlo method to simulate the dynamics of this coordinated movement. Based on four essential assumptions, our simulations reproduce some features of the recent in vivo experiments. The fast moving speed of the cargo is simulated and the speed distribution is presented.
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| 关 键 词： | 分子马达 动力蛋白 蒙特卡洛模拟 细胞分裂 |
| 收稿时间： | 2007-04-10 |
Monte Carlo Simulation on Coordinated Movement of Kinesin and Dynein Motors |
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| WANG Hong,DOU Shuo-Xing,WANG Peng-Ye.Monte Carlo Simulation on Coordinated Movement of Kinesin and Dynein Motors[J].Chinese Physics Letters,2008,25(1):321-324. |
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| Authors: | WANG Hong DOU Shuo-Xing WANG Peng-Ye |
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| Affiliation: | Laboratory of Soft Matter Physics, Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100080 |
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| Abstract: | Kinesin and dynein are two important classes of molecular motors which are responsible for active organelle trafficking and cell division. They can work together to carry a cargo, moving along the microtubule in a coordinated way. We use Monte Carlo method to simulate the dynamics of this coordinated movement. Based on four essential assumptions, our simulations reproduce some features of the recent in vivo experiments. The fast moving speed of the cargo is simulated and the speed distribution is presented. |
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| Keywords: | 87 16 Nn 87 16 Ac |
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