Selective Functionalization of Hollow Nanospheres with Acid and Base Groups for Cascade Reactions |
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| Authors: | Dr Jinsuo Gao Xueying Zhang Yong Lu Prof Shaomin Liu Dr Jian Liu |
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| Affiliation: | 1. Key Laboratory of Industrial Ecology and Environmental Engineering (MOE), School of Environmental Science and Technology, State Key Laboratory of Fine Chemicals, Dalian University of Technology, Linggong Road 2, Dalian 116024 (P. R. China);2. Department of Chemical Engineering, Curtin University, Perth, WA 6845 (Australia) |
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| Abstract: | The inner‐surface functionalization of hollow silica spheres has rarely been reported and is still a challenging topic. Herein, we report a deacetalization–Henry cascade reaction catalyzed by dual‐functionalized mesoporous silica hollow nanospheres with basic amine groups (?NH2) on the internal shell and carboxylic acid groups (?COOH) on the external shell. The selective functionalization has been realized by a combination of “step‐by‐step post‐grafting” and “cationic surfactant‐assisted selective etching” strategy. Compared to unisolated catalyst, the selectively isolated acidic and basic dual catalyst provides excellent catalytic performance for the deacetalization–Henry cascade reaction in terms of both activity (>99 %) and selectivity (95 %). |
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| Keywords: | cascade reaction hollow nanosphere nanostructures mesoporous materials selective functionalization |
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