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嘌呤2位卤素取代衍生物的合成
引用本文:陆鸿飞,陆明,章丽娟.嘌呤2位卤素取代衍生物的合成[J].应用化学,2006,23(10):1156-0.
作者姓名:陆鸿飞  陆明  章丽娟
作者单位:南京理工大学化工学院
摘    要:嘌呤2位卤素取代衍生物的合成;嘌呤;重氮化;合成;杀菌活性

关 键 词:嘌呤2位卤素取代衍生物的合成  嘌呤  重氮化  合成  杀菌活性  
文章编号:1000-0518(2006)10-1156-05
收稿时间:2005-11-16
修稿时间:2006-01-12

Syntheses of 2-Halogenopurine Derivatives
LU Hong-Fei,LU Ming,ZHANG Li-Juan.Syntheses of 2-Halogenopurine Derivatives[J].Chinese Journal of Applied Chemistry,2006,23(10):1156-0.
Authors:LU Hong-Fei  LU Ming  ZHANG Li-Juan
Institution:College of Chemistry Engineering, Nanjing University of Science and Technology, Nanjing 210094
Abstract:A series of 2-halogenopurine derivatives was synthesized from guanine through diazotization.All the products were characterized by ~(1)H NMR,MS and elemental analysis.Fungicidal activities of all the(compounds) were tested.Good fungicidal activity was observed for 5a,5c,5g and 5h against Bacillus subtillis,5b and 5c against Aspergillus niger,and 5f against Cardida tropicals.Density functions of all the compounds were calculated using Gaussian 98,and the effect of different groups on the net charges of C(2) were(discussed).
Keywords:purine  diazotization  synthesis  fungicidal activity
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