Spectrophotometric determination of zinc in pharmaceutical preparations with biacetyl mono(2-pyridyl)-hydrazone |
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Authors: | AG Asuero D Rosales MM Rodriguez |
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Institution: | Department of “Bromatologia,” Toxicology and Applied Chemical Analysis, Faculty of Pharmacy, The University of Seville, Seville-4, Spain |
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Abstract: | The biacetyl mono(2-pyridyl)hydrazone (BPH) spectrophotometric procedure for zinc (λmax = 440 nm, ? = 52,100 liters mol?1 cm?1, 1 ml BPH at 0.25% in ethanol/25 ml, 20% of ethanol as medium, boric acid/sodium hydroxide, pH 10, buffer) has been applied to the determination of zinc in pharmaceutical preparations (ophthalmic solutions, mouthwash liquids, and cream ointments) with good results. |
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