Total synthesis of (-)-spongidepsin |
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Authors: | Ferrié Laurent Reymond Sébastien Capdevielle Patrice Cossy Janine |
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Institution: | ESPCI, Laboratoire de Chimie Organique, 10 Rue Vauquelin, 75231 Paris Cedex 05, France. |
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Abstract: | structure: see text] A convergent and rapid stereoselective synthesis of (-)-spongidepsin has been achieved from the Roche ester in 14 steps with an overall yield of 13%. |
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