Biological chemistry of organotin compounds: Interactions and dealkylation by dithiols |
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| Authors: | Bethany A Buck-Koehntop John L Lewin Gianluigi Veglia |
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| Institution: | a Department of Chemistry and Supercomputing Institute, University of Minnesota, 207 Pleasant St. SE, Minneapolis, MN 55455, United States
b Department of Environmental Sciences (Di.S.A.), University of Tuscia, Viterbo, Italy |
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| Abstract: | In this paper, we review our past and current efforts toward the elucidation of the biological chemistry of organotin compounds. In particular, we cover two prominent aspects of organotin compounds: their reactivity toward biological dithiols, and their degradation (or metabolization) mechanism using a combination of experimental and computational techniques. |
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| Keywords: | Organotin(IV) compounds Stannin NMR CD spectroscopy ESI-MS Fluorescence spectroscopy |
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