Synthesis of novel 9-(1-iodovinyl)acridin-(2H)-one through iodine mediated cascade 6-endo-dig cyclization followed by condensation and 3,3-sigmatropic migration of 2-aminophenyl propynyl oxyenone |
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| Authors: | Mahalingam SivaramanDoraiswamy Muralidharan Paramasivan T Perumal |
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| Institution: | Organic Chemistry Division, Central Leather Research Institute, Adyar, Chennai 600020, Tamilnadu, India |
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| Abstract: | An efficient and rapid synthetic strategy for the construction of a pharmaceutically important acridinone scaffold via cascade iodocyclization of functionally substituted 2-aminophenyl propynyl oxyenone is developed. |
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| Keywords: | Acridinone Cascade Iodocyclization Alkyne |
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