|
|||||
|
|
The first stereoselective total synthesis of the Z-isomer of cytospolide E |
|
| Authors: | J.S. Yadav T. PandurangamA. Suman Kumar P. Adi Narayana ReddyA.R. Prasad B.V. Subba ReddyK. Rajendraprasad A.C. Kunwar |
| Affiliation: | a Natural Product Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India b Center for Nuclear Magnetic Resonance, Indian Institute of Chemical Technology, Hyderabad 500 007, India |
| Abstract: | A convergent and highly stereoselective total synthesis of the Z-isomer of cytospolide E has been achieved via Evan’s aldol reaction, Sharpless kinetic resolution and RCM cyclisation. |
| Keywords: | Cytotoxic Macrolide Evan&rsquo s aldol Ring closing metathesis |
| 本文献已被 ScienceDirect 等数据库收录！ | |