One-pot two step synthesis of unsymmetrically substituted indenes from 3,4-diarylbutadiene sulfones |
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| Affiliation: | A.V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, 119991 Moscow, Russian Federation |
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| Abstract: | A new one-pot two step synthesis of unsymmetrically substituted indenes from available 3,4-diarylbutadiene sulfones involves SO2 thermal extrusion followed by acid- catalyzed cyclization of the diene formed, the cyclization proceeding selectively at the more electron-rich aryl rings. The procedure is efficient for substrates bearing donor, acceptor, as well as bulky substituents. |
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| Keywords: | indenes 34-diarylbutadienes sulfones sulfur dioxide thermal extrusion catalytic cyclization Friedel–Crafts reaction one-pot synthesis |
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