Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives |
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Authors: | Zhang Liu Lili OuMarc A Giulianotti Richard A Houghten |
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Institution: | Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, FL 34987, USA |
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Abstract: | An efficient solid-phase synthetic approach for the synthesis of N-substituted 3, 4-dihydroquinazolinone derivatives has been developed. Four different 2-nitrobenzoic acids and three different 2-phenylacetyl chlorides were employed in the synthesis of this library. After purification, all products were obtained in good yields. |
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