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Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives
Authors:Zhang Liu  Lili OuMarc A Giulianotti  Richard A Houghten
Institution:Torrey Pines Institute for Molecular Studies, 11350 SW Village Parkway, Port St. Lucie, FL 34987, USA
Abstract:An efficient solid-phase synthetic approach for the synthesis of N-substituted 3, 4-dihydroquinazolinone derivatives has been developed. Four different 2-nitrobenzoic acids and three different 2-phenylacetyl chlorides were employed in the synthesis of this library. After purification, all products were obtained in good yields.
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