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Catalyst and solvent-free amidation of inactive esters of N-protected amino acids |
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| Authors: | Krishna Chaitanya NadimpallyKishore Thalluri Nani Babu PalakurthyAbhijit Saha Bhubaneswar Mandal |
| Affiliation: | Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India |
| Abstract: | A catalyst free procedure for the preparation of amides from inactive esters of N-protected amino acids and various amines is demonstrated under mild reaction conditions. Our effort to recover excess amine and generated alcohol is an approach towards environment friendly and cost effective synthesis under easy operational conditions. |
| Keywords: | Aminolysis Inactive esters Amino acid Amidation |
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