Lab-chip HPLC with integrated droplet-based microfluidics for separation and high frequency compartmentalisation |
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| Authors: | Jin-Young Kim Soong-Won Cho Dong-Ku Kang Joshua B Edel Soo-Ik Chang Andrew J Demello Danny O'Hare |
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| Institution: | Department of Bioengineering, Imperial College London, London SW7 2AZ, UK. d.ohare@imperial.ac.uk. |
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| Abstract: | We demonstrate the integration of a droplet-based microfluidic device with high performance liquid chromatography (HPLC) in a monolithic format. Sequential operations of separation, compartmentalisation and concentration counter were conducted on a monolithic chip. This describes the use of droplet-based microfluidics for the preservation of chromatographic separations, and its potential application as a high frequency fraction collector. |
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