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Nanoplasmonic detection of adenosine triphosphate by aptamer regulated self-catalytic growth of single gold nanoparticles
Authors:Qing Liu  Chao Jing  Xiaoxue Zheng  Zhen Gu  Di Li  Da-Wei Li  Qing Huang  Yi-Tao Long  Chunhai Fan
Affiliation:State Key Laboratory of Bioreactor Engineering & Department of Chemistry, East China University of Science and Technology, Shanghai, 200237, China. ytlong@ecust.edu.cn.
Abstract:We present a nanoplasmonic aptasensor for adenosine triphosphate (ATP) by using single gold nanoparticles (GNPs) as probes. The specific aptamer-ATP binding induced conformational change could modulate the surface-dependent self-catalytic growth of GNPs, which enabled the detection of ATP with ultra-sensitivity and selectivity.
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