Nanoplasmonic detection of adenosine triphosphate by aptamer regulated self-catalytic growth of single gold nanoparticles |
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Authors: | Qing Liu Chao Jing Xiaoxue Zheng Zhen Gu Di Li Da-Wei Li Qing Huang Yi-Tao Long Chunhai Fan |
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Affiliation: | State Key Laboratory of Bioreactor Engineering & Department of Chemistry, East China University of Science and Technology, Shanghai, 200237, China. ytlong@ecust.edu.cn. |
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Abstract: | We present a nanoplasmonic aptasensor for adenosine triphosphate (ATP) by using single gold nanoparticles (GNPs) as probes. The specific aptamer-ATP binding induced conformational change could modulate the surface-dependent self-catalytic growth of GNPs, which enabled the detection of ATP with ultra-sensitivity and selectivity. |
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