Metal-alloy-dispersed carbon-paste enzyme electrodes for amperometric biosensing of glucose |
| |
| Institution: | 1. International Diabetes Center at Park Nicollet Clinic, Minneapolis, MN;2. BD Diabetes Care, Franklin Lakes, NJ;1. Brains On-Line BV, Groningen, the Netherlands;2. University of Groningen Institute of Pharmacy, Groningen, the Netherlands;3. Brains On-Line LLC, San Francisco, California, USA;1. Institut d’Electronique, de Microélectronique et de Nanotechnologie (IEMN), CNRS UMR8520, The University of Lille, Cité Scientifique, Avenue Poincaré, 59652, Villeneuve d''Ascq, France;2. Univ. Lille, Inserm, CHU Lille, U1172 - LilNCog - Lille Neuroscience & Cognition, F59000, Lille, France;1. Department of Biomedical Engineering, National Cheng Kung University, Tainan, Taiwan;2. Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, Taiwan;3. Biomedical Engineering and System Bioinformatics Research Center, Kaohsiung Medical University, Taiwan;4. Medical Device Innovation Center (MDIC), National Cheng Kung University, Tainan, Taiwan;5. National Applied Research Laboratories, Taipei 106, Taiwan |
| |
| Abstract: | The preferential electrocatalytic detection of hydrogen peroxide and the selective biosensing of glucose at carbon-paste enzyme electrodes dispersed with bimetallic (Ru–Pt) alloy particles are described. Unlike the marked acceleration of the redox reaction of the peroxide product (versus single metal catalysts), the signals of common interfering compounds shift to higher potentials. Such use of carbon-supported alloy particles thus results in a greatly enhanced sensitivity compared to the dispersion of pure metals, without compromising the remarkable selectivity inherent to metallized carbon biosensors. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
