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The role of proficiency testing in method validation
Abstract:The general principle of using data collected during proficiency testing (PT) for the additional purpose of assessing method performance is discussed. Particular attention is paid to the similarities and differences in conduct of traditional interlaboratory method performance studies and proficiency testing. Recommendations are made for implementing PT-based method performance studies, including statistical assessment of the data. It is concluded that, properly implemented, PT-based method performance study provides essentially equivalent information to that obtained from traditional collaborative study and may be used in appraising candidate methods with a view to their adoption as standard methods.
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