Silica sulfuric acid-catalyzed Claisen-Schmidt condensation of 1,3,4 trisubstituted pyrrole 2,5 dione to chalcones |
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| Authors: | J. R. Patel M. H. Malani B. Z. Dholakiya |
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| Affiliation: | 1. Department of Applied Chemistry, S.V. National Institute of Technology, Ichhanath, Surat, 395007, Gujarat, India
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| Abstract: | A series of 11 chalcones was synthesized from 1-(4-acetylphenyl)-3,4-dibromo-1H-pyrrole-2,5-dione with various substituted benzaldehyde under solvent-free conditions using silica-sulphuric acid as a catalyst. The yields of chalcones are more than 90 %. All the compounds were characterized by physical, spectroscopic, and elemental analysis. |
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