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Synthesis,characterization and biological activity studies of octahedral nickel(II) complexes
Authors:Ram N Patel  Anurag Singh  Krishna K Shukla  Dinesh K Patel  Vishnu P Sondhiya
Institution:(1) Department of Chemistry, A. P. S. University, Rewa, 486003, Madhya Pradesh, India
Abstract:

Abstract  

Three nickel(II) complexes, namely Ni(BH)3](H2O)(NO3)(ClO4) 1, Ni(BH)2(NO3)2] 2 and Ni(BH)(Tren)](ClO4)2 3 (BH = Benzoylhydrazine, Tren = Tris(2-aminoethyl)amine) have been synthesized and characterized by physico-chemical techniques. X-ray crystallographic analysis shows the nickel to be six-coordinated in these complexes. The complexes are efficient catalysts for the dismutation of superoxide in alkaline DMSO-NBT assays. The IC50 values are 74,108 and 105 μM for 1, 2 and 3, respectively.
Keywords:
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