Synthesis,structure, and DNA-binding properties of manganese(II) and zinc(II) complexes with tris(<Emphasis Type="Italic">N</Emphasis>-methylbenzimidazol-2-ylmethyl)amine ligand |
| |
Authors: | Hui-Lu Wu Ke Li Tao Sun Fan Kou Fei Jia Jing-Kun Yuan Bin Liu Bao-Liang Qi |
| |
Institution: | (1) School of Chemical and Biological Engineering, Lanzhou Jiaotong University, 730070 Lanzhou, Gansu, China |
| |
Abstract: | Tris(N-methylbenzimidazol-2-ylmethyl)amine (Mentb) and its two complexes, Mn(Mentb)(DMF)(H2O)](pic)2
1 and Zn(Mentb)(pic)](pic) 2 (pic = picrate), have been synthesized and characterized by physico-chemical and spectroscopic methods. Single crystal X-ray
diffraction revealed that the two complexes have different structures. In complex 1, the coordination sphere around Mn(II) is distorted octahedral, whereas in complex 2 the coordination sphere around Zn(II) is distorted trigonal bipyramidal. The DNA-binding properties of the free ligand and
its two complexes have been investigated by electronic absorption, fluorescence, and viscosity measurements. The results suggest
that the ligand and its two complexes bind to DNA via an intercalation binding mode, and their binding affinity for DNA follows
the order 1 > 2 > ligand. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|