| Synthesis of protected （2S,4R）-2-amino-4-methyldecanoic acid,a proposed component of culicinins |
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| 引用本文： | Wei Zhang Tian Tian Sun Duo Mei Jun Fei Wang Ying Xia Li. Synthesis of protected （2S,4R）-2-amino-4-methyldecanoic acid,a proposed component of culicinins[J]. 中国化学快报, 2008, 19(9): 1068-1070. DOI: 10.1016/j.cclet.2008.06.027 |
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| 作者姓名： | Wei Zhang Tian Tian Sun Duo Mei Jun Fei Wang Ying Xia Li |
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| 作者单位： | Key laboratory of Marine Drugs, The Ministry of Education of China, School of Pharmacy, Ocean University of China, Qingdao 266003, China |
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| 基金项目： | 国家自然科学基金，国家高技术研究发展计划(863计划)，Excellent Young Scientists Foundation of Shandong Province |
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| 摘 要： | The protected （2S,4R）-2-amino-4-methyldecanoic acid, a proposed component of culicinins has been synthesized over 10 steps and in total 28% yields using Wittig reaction and Schollkopf amino acid synthesis as key steps.
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| 关 键 词： | Synthesis Amino acid SehÖ llkopf methodology Culicinins |
| 收稿时间： | 2008-03-27 |
Synthesis of protected (2S,4R)-2-amino-4-methyldecanoic acid, a proposed component of culicinins |
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| Wei Zhang,Tian Tian Sun,Duo Mei,Jun Fei Wang,Ying Xia Li. Synthesis of protected (2S,4R)-2-amino-4-methyldecanoic acid, a proposed component of culicinins[J]. Chinese Chemical Letters, 2008, 19(9): 1068-1070. DOI: 10.1016/j.cclet.2008.06.027 |
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| Authors: | Wei Zhang Tian Tian Sun Duo Mei Jun Fei Wang Ying Xia Li |
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| Affiliation: | Key laboratory of Marine Drugs, The Ministry of Education of China, School of Pharmacy, Ocean University of China, Qingdao 266003, China |
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| Abstract: | The protected (2S,4R)-2-amino-4-methyldecanoic acid, a proposed component of culicinins has been synthesized over 10 steps and in total 28% yields using Wittig reaction and Schollkopf amino acid synthesis as key steps. |
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| Keywords: | Synthesis Amino acid Sehollkopf methodology Culicinins |
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