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Caco-2 cell permeability modelling: a neural network coupled genetic algorithm approach |
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| Authors: | Armida Di Fenza Giuliano Alagona Caterina Ghio Riccardo Leonardi Alessandro Giolitti Andrea Madami |
| Affiliation: | (1) Molecular Modelling Lab, Institute for Physico-Chemical Processes (IPCF) - CNR, Via G. Moruzzi 1, 56124 Pisa, Italy;(2) Ion Trading s.r.l., Via S. Martino 52, 56125 Pisa, Italy;(3) Menarini Ricerche SpA, Via Sette Santi 3, 50131 Firenze, Italy;(4) Menarini Ricerche SpA, Via Tito Speri 10, 00040 Pomezia, Roma, Italy |
| Abstract: | |
| Keywords: | Neural network Genetic algorithm Caco-2 cell permeability Intestinal absorption Oral bioavailability |
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