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Synthesis of the 6′-iso analogues of neplanocin A and 5′-homoneplanocin A
Authors:Wei Ye
Institution:Department of Chemistry and Biochemistry, Auburn University, Auburn, AL 36849-5312, United States
Abstract:An efficient synthesis of 6′-isoneplanocin A and 6′ -isohomoneplanocin A is reported. The key steps in the synthesis include an enyne metathesis and a regioselective oxidation.
Keywords:Carbocyclic nucleosides  Grubbs reaction  Mitsunobu reaction
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