Synthesis of the 6′-iso analogues of neplanocin A and 5′-homoneplanocin A |
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Authors: | Wei Ye |
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Institution: | Department of Chemistry and Biochemistry, Auburn University, Auburn, AL 36849-5312, United States |
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Abstract: | An efficient synthesis of 6′-isoneplanocin A and 6′ -isohomoneplanocin A is reported. The key steps in the synthesis include an enyne metathesis and a regioselective oxidation. |
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Keywords: | Carbocyclic nucleosides Grubbs reaction Mitsunobu reaction |
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