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First asymmetric total synthesis of aspinolide A
Authors:Partha Sarathi Chowdhury
Affiliation:Organic Chemistry Division, National Chemical Laboratory, Pune 411 008, India
Abstract:The first total synthesis of aspinolide A has been achieved using ring-closing metathesis as a key step. The stereogenic centers were generated by means of hydrolytic kinetic resolution (HKR) of racemic epoxides.
Keywords:Decanolides   Hydrolytic kinetic resolution   Ring-closing metathesis   Epoxides
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