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Enantioselective synthesis of decarestrictine J
Authors:Partha Sarathi Chowdhury
Institution:Organic Chemistry Division, National Chemical Laboratory, Pune 411 008, India
Abstract:An efficient total synthesis of decarestrictine J has been achieved using ring-closing metathesis and Yamaguchi esterification as key steps. The stereogenic centres were generated by means of iterative hydrolytic kinetic resolution (HKR) of racemic epoxides.
Keywords:Decanolides  Hydrolytic kinetic resolution  Yamaguchi esterification  Ring-closing metathesis  Epoxides
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