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Atom-efficient and environment-friendly multicomponent synthesis of amidoalkyl naphthols catalyzed by P2O5
Authors:Ganesh Chandra Nandi
Affiliation:Department of Chemistry, Faculty of Science, Banaras Hindu University, Varanasi 221 005, India
Abstract:An atom-efficient and environment-friendly approach for the synthesis of amidoalkyl naphthols (4a-x) via multicomponent one-pot reaction of 2-naphthol (1), aromatic aldehyde (2) and amide (3) catalyzed by P2O5 has been developed. The present approach offers several advantages such as reduced reaction times, moderate temperature, higher yields, eco-friendly reaction condition, easy purification and economic availability of the catalyst.
Keywords:Multicomponent reaction   Amidoalkyl naphthols   P2O5   Solvent free one-pot synthesis   Moderate temperature
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