Facile N-formylation of amines using Lewis acids as novel catalysts |
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Authors: | A. Chandra Shekhar |
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Affiliation: | Fluoroorganics Division, Indian Institute of Chemical Technology, Hyderabad 500 607, India |
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Abstract: | Alky, aryl, and heteroaryl amines were found to react efficiently with formic acid under Lewis acid catalysis giving N-formyl derivatives in high yields. A study of ZnCl2-catalyzed N-formylation of a variety of amines using formic acid as formylating agent is described. |
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Keywords: | N-Formylation Amines Formic acid Lewis acid |
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