1, 1-Difluoro-1H-cyclopropa[a]naphthalene |
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Authors: | Paul Mü ller,Huong-Can Nguyen-Thi |
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Abstract: | 1, 1-Difluorocyclopropa[a]naphthalene ( 1b ) is prepared in three steps from 4-bromo-1,2-dihydronaphthalene ( 7 ) via carbene addition, benzylic bromination and bidehydrohalogenation. Structural evidence for formation of 1b is based on 1H- and 19F-NMR spectroscopy. Compound 1b is stable in solution at ?30°. Upon reaction with MeOH/H+ it is converted to a 1:2 mixture of 1- and 2-methylnaphthoate ( 10 and 11 , respectively). |
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