Synthesis and biological activities of N-(1,2,4-triazole-4-yl)-N′-(fluorine-containing-phenyl)carbamimidothioates |
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| Authors: | Dawei CuiZhibin Li Gonghua Song Xuhong Qian |
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| Institution: | Institute of Pesticides and Pharmaceuticals, East China University of Science and Technology, P.O. Box 544, 130 Meilong Road, Shanghai 200237, PR China |
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| Abstract: | A series of N-(1,2,4-triazole-4-yl)-N′-(fluorine-containing-phenyl)carbamimidothioates 5a-i were synthesized by reacting 4-amine-1,2,4-trizaole with corresponding aryl isothiocyanates in ethanol at room temperature and, in a subsequent step, with methyl iodide. The antifungal activities of the title compounds against the fungi Rhizoctonia solan and Pyricularia orizae were screened. |
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| Keywords: | Synthesis Biological activity N-(1 2 4-Triazole-4-yl)-N&prime -(fluorine-containing-phenyl)carbamimidothioates |
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