Synthesis of fluorinated amphiphiles by the reaction of protected hydroxy carbaldehyde with perfluorinated organomagnesium compounds |
| |
| Affiliation: | Department of Organic Chemistry, Institute of Chemical Technology, Technická 5, 166 28 Prague 6, Czech Republic |
| |
| Abstract: | Fluorinated amphiphilic compounds with enhanced chemical stability were synthesized by the reaction of 5-(2,2,5-trimethyl-1,3-dioxane)carbaldehyde (1) with perfluoroalkylmagnesium bromides (2), followed by deprotection. The key aldehyde 1 was prepared by Swern oxidation of 5-(2,2,5-trimethyl-1,3-dioxane)methanol (3). |
| |
| Keywords: | Fluorophilic Amphiphilic Polyfluorinated polyol Grignard reaction Perfluoroalkylmagnesium iodide Polyfluoroorganometallic Nucleophilic addition |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
