Development of an Iron(II)‐Catalyzed Aerobic Catechol Cleavage and Biomimetic Synthesis of Betanidin |
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| Authors: | Dr Nicolas Guimond Dr Peter Mayer Prof Dr Dirk Trauner |
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| Institution: | Department of Chemistry, Ludwig‐Maximilians University Munich and Center for Integrated Protein Science, Butenandstrasse 5–13, 81377 Munich (Germany), Fax: (+49)?89‐2180‐77972 |
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| Abstract: | An aerobic iron(II)‐catalyzed cleavage of catechols was developed. This reaction allows for the preparation of 2‐methoxy‐2 H‐pyrans that can be employed as versatile building blocks for synthesis. The utility of this biomimetic oxidative cleavage is featured in the synthesis of betanidin, a natural colorant with antioxidant properties. |
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| Keywords: | aerobic oxidation betalain biomimetic synthesis green chemistry iron |
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