Ruthenium(II)‐Catalyzed Oxidative CH Alkenylations of Sulfonic Acids,Sulfonyl Chlorides and Sulfonamides |
| |
Authors: | Wenbo Ma Ruhuai Mei Giammarco Tenti Prof. Dr. Lutz Ackermann |
| |
Affiliation: | Institut für Organische und Biomolekulare Chemie, Georg‐August‐Universit?t, Tammannstra?e 2, 37077 G?ttingen (Germany) |
| |
Abstract: | Twofold C?H functionalization of aromatic sulfonic acids was achieved with an in situ generated ruthenium(II) catalyst. The optimized cross‐dehydrogenative alkenylation protocol proved applicable to differently substituted arenes and a variety of alkenes, including vinyl arenes, sulfones, nitriles and ketones. The robustness of the ruthenium(II) catalyst was demonstrated by the chemoselective oxidative olefination of sulfonamides as well as sulfonyl chlorides. Mechanistic studies provided support for a reversible, acetate‐assisted C?H ruthenation, along with a subsequent olefin insertion. |
| |
Keywords: | alkenes C H activation reaction mechanism ruthenium sulfonic acids |
|
|