Structure and properties of complexes of polycationic brushes with anionic liposomes |
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| Authors: | O. V. Zaborova A. V. Sybachin M. Ballauff A. A. Yaroslavov |
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| Affiliation: | 1.Faculty of Chemistry,Moscow State University,Moscow,Russia;2.Department of Physics,Humboldt University,Berlin,Germany;3.Helmholtz-Zentrum Berlin für Materialien und Energie,Berlin,Germany |
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| Abstract: | The adsorption of anionic lipid vesicles (liposomes) on the surfaces of colloidal particles containing grafted polycationic chains (cationic brushes) is studied. The stability of liposome-brush complexes in aqueous salt solutions increases with the content of anionic lipid in the liposomal membrane; complexes with liposomes containing 20 and 30 mol% anionic lipids do not dissociate into individual components in a 1.2 M NaCl solution. The integrity of the brush-bound liposomes is preserved. The developed approach can be used to obtain nanosized carriers for biologically active compounds. |
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