Crystal structure of sulfamerazine |
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| Authors: | K Ravindra Acharya K N Kuchela Gopinath Kartha |
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| Institution: | (1) Department of Physics, Central College, Bangalore University, 560 001 Bangalore, India;(2) New York State Department of Health, Roswell Park Memorial Institute, 14263 Buffalo, New York |
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| Abstract: | The structure of sulfamerazine, C11H12N4O2S, a very important sulfonamide drug, has been solved by direct methods with X-ray diffraction data collected using CuK radiation. The crystals are orthorhombic, witha=9.145(1),b=11.704(1),c=22.884(2) Å and space groupPbca. The structure was refined with 2082 observed independent reflections, measured on a CAD-4 diffractometer, to a finalR value of 0.078. The molecule has similar conformational features to those observed in other sulfonamide drugs. |
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