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One‐Pot Multicomponent Synthesis of β‐Amino Amides
Abstract:Multicomponent reactions are excellent tools for rapid generation of small molecules with broad chemical diversity and molecular complexity. Herein, a novel one‐pot multicomponent synthesis of β‐amino amides from aldehydes, anilines, carboxylic acids and ynamides has been successfully developed. This process is practical and efficient to unravel synthetic utility and scalability. Moreover, an isotope labeling reaction was conducted to elucidate a plausible reaction mechanism.
Keywords:Aminosä  uren  Inamide  Mehrkomponentenreaktionen  Molekulare Diversitä  t  Tandemreaktionen
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