A mass spectrometric study of 4-hydroxy-6-methyl-2-pyridone and its derivatives |
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Authors: | N S Wulfson V G Zaikin Z S Ziyavidinova V M Burikov S K Mukerjee |
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Institution: | Institute for Chemistry of Natural Products, USSR Academy of Sciences, Moscow, USSR |
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Abstract: | The mass spectra of 4-hydroxy-6-methyl-2-pyridone, its N-methyl and N-phenyl derivatives, and also their 4-O-acetyl and 3-C-acyl derivatives have been studied. The proposed fragmentation pathways were supported by comparison of the mass spectra and in some cases by the spectra of deutero analogues. A strong N-phenyl group effect has been found, which in the case of N-phenyl-4-hydroxy- and N-phenyl-4-acetoxy-6-methyl-2-pyridones promotes the formation of the stable M—H]+ and M—CH3CO]+ ions respectively. These ions are not characteristic of the N—H and N—Me analogues. |
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