Über die Synthese von 1,4-Benzoxazepinen und ihre Umlagerung in Isochinoline

The syntheses of 3-phenyl-5-oxo-4, 5-dihydro-1,4-benzoxazepine ( 2 ) and -3-phenyl-5-ethoxy-1,4-benzoxazepine ( 14 ) are described. 2 rearranges under the influence of sodamide into the isoquinoline derivatives 4 , 5 and 6 respectively; 14 is converted quantitatively into 1-ethoxy-3-phenyl-4-hydroxy-isoquinoline ( 16 ) in boiling methanol, even in the absence of a strong base. Possible reaction mechanisms are discussed.