Structure of magnetically guided nanocarriers of the photodithazine sensitizer from small-angle neutron scattering data |
| |
| Authors: | Yu.?V.?Kulvelis V.?A.?Trounov V.?T.?Lebedev D.?N.?Orlova Gy.?T?r?k M.?L.?Gelfond |
| |
| Affiliation: | (3) Department of Pharmaceutical Sciences, University of Missouri-Kansas City, 5005 Rockhill Road, Kansas City, MO 64110, USA |
| |
| Abstract: | Nanosized complexes of ferromagnetic particles with a photodithazine sensitizer (used in photo-dynamic therapy in oncology) have been synthesized and investigated using small-angle neutron scattering for the first time. The structure of the complexes has been determined, and the influence of the biocompatible polymer Pluronic on their structure has been analyzed. The possibilities of using the complexes for magnetically guided delivery of the photosensitizer to cells and tissues in the treatment of oncological diseases by photodynamic therapy have been discussed. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
