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Drimane sesquiterpenoids from the mangrove-derived fungus Aspergillus ustus
Authors:Zhou Huinan  Zhu Tianjiao  Cai Shengxin  Gu Qianqun  Li Dehai
Affiliation:Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, P.R. China.
Abstract:Five new drimane sesquiterpenes (1-5) together with 14 known analogues (6-19) were isolated from laboratory cultures of a mangrove-derived fungus Aspergillus ustus. Their structures were established by spectroscopic methods and antitumor activities were evaluated by sulforhodamine B (SRB) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) methods.
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