Drimane sesquiterpenoids from the mangrove-derived fungus Aspergillus ustus |
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Authors: | Zhou Huinan Zhu Tianjiao Cai Shengxin Gu Qianqun Li Dehai |
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Affiliation: | Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, P.R. China. |
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Abstract: | Five new drimane sesquiterpenes (1-5) together with 14 known analogues (6-19) were isolated from laboratory cultures of a mangrove-derived fungus Aspergillus ustus. Their structures were established by spectroscopic methods and antitumor activities were evaluated by sulforhodamine B (SRB) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) methods. |
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